Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.34 |
| ▸ | BAZ1A | Q9NRL2 | 1/20 | 0.31 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27837726 | 0.85 | ALDH1A1 (0.34) | — | |
| SCHEMBL4908387 | 0.76 | ALDH1A1 (0.42) | HCAR2 | |
| SCHEMBL29728017 | 0.76 | ALDH1A1 (0.42) | HCAR2 | |
| SCHEMBL5233339 | 0.73 | CYP2A6 (0.54) | — | |
| SCHEMBL5073476 | 0.71 | DAPK3 (0.49) | — | |
| SCHEMBL30396687 | 0.71 | DAPK3 (0.49) | — | |
| SCHEMBL6224494 | 0.71 | POLB (0.42) | — | |
| SCHEMBL4795893 | 0.70 | CYP2A6 (0.54) | — | |
| SCHEMBL4710923 | 0.69 | ALDH1A1 (0.34) | — | |
| SCHEMBL18342663 | 0.67 | EGFR (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3055313-A1 | CYCLIC THIENOURACIL-CARBOXAMIDES AND USE THEREOF | Bayer Pharma Aktiengesellschaft (DE) | 2016-08-17 | — | — | EP | disclosed |
| WO-2015052065-A1 | CYCLIC THIENOURACIL-CARBOXAMIDES AND USE THEREOF | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2015-04-16 | — | — | WO | disclosed |