Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 3/20 | 0.55 |
| ▸ | CLK2 | P49760 | 3/20 | 0.55 |
| ▸ | CLK4 | Q9HAZ1 | 3/20 | 0.55 |
| ▸ | STK17A | Q9UEE5 | 3/20 | 0.55 |
| ▸ | IRAK1 | P51617 | 2/20 | 0.55 |
| ▸ | NEK4 | P51957 | 2/20 | 0.55 |
| ▸ | MAP4K2 | Q12851 | 2/20 | 0.55 |
| ▸ | HIPK4 | Q8NE63 | 2/20 | 0.55 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.55 |
| ▸ | SRPK1 | Q96SB4 | 1/20 | 0.55 |
| ▸ | MAP3K20 | Q9NYL2 | 1/20 | 0.55 |
| ▸ | MAP4K5 | Q9Y4K4 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | GCK | P35557 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | RIOK2 | Q9BVS4 | 1/20 | 0.51 |
| ▸ | IDH2 | P48735 | 3/20 | 0.50 |
| ▸ | FBP1 | P09467 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12203066 | 0.86 | GCK (0.54) | KDRCLK2CLK4STK17AIRAK1 | |
| SCHEMBL9475450 | 0.84 | GCK (0.52) | KDRCLK2CLK4STK17AIRAK1 | |
| SCHEMBL3192275 | 0.84 | L3MBTL1 (0.55) | KDRCLK2CLK4STK17AIRAK1 | |
| SCHEMBL31264157 | 0.82 | ALDH1A1 (0.56) | KDRCLK2CLK4STK17AIRAK1 | |
| SCHEMBL2635853 | 0.82 | ALDH1A1 (0.56) | KDRCLK2CLK4STK17AIRAK1 | |
| SCHEMBL29128686 | 0.82 | KDR (0.50) | KDRCLK2CLK4STK17AIRAK1 | |
| SCHEMBL25406525 | 0.81 | KDR (0.71) | KDRCLK2CLK4STK17AIRAK1 | |
| SCHEMBL16253003 | 0.81 | AR (0.58) | KDRCLK2CLK4STK17AIRAK1 | |
| SCHEMBL30875900 | 0.81 | NR3C2 (0.67) | KDRCLK2CLK4STK17AIRAK1 | |
| SCHEMBL5029590 | 0.81 | NR3C2 (0.67) | KDRCLK2CLK4STK17AIRAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4568951-A1 | HETEROCYCLIC AMIDE AND UREA COMPOUNDS AS JAK2 INHIBITORS | AJAX THERAPEUTICS, INC. (US) | 2025-06-18 | — | — | EP | disclosed |
| WO-2024035627-A1 | HETEROCYCLIC AMIDE AND UREA COMPOUNDS AS JAK2 INHIBITORS | AJAX THERAPEUTICS, INC. (US) | 2024-02-15 | — | — | WO | disclosed |
| US-11608323-B2 | Herbicidal compounds | SYNGENTA PARTICIPATIONS AG (CH) | 2023-03-21 | — | — | US | disclosed |
| EP-3054773-B1 | HERBICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2022-01-26 | — | — | EP | disclosed |
| EP-3054773-B1 | HERBICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2022-01-26 | — | — | EP | disclosed |
| CN-111961033-A | Herbicidal compounds | 先正达参股股份有限公司 | 2020-11-20 | — | — | CN | disclosed |
| US-20190112288-A1 | HERBICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2019-04-18 | — | — | US | disclosed |
| US-20190112288-A1 | HERBICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2019-04-18 | — | — | US | disclosed |
| US-20180092358-A1 | HERBICIDAL MIXTURES | SYNGENTA PARTICIPATIONS AG (CH) | 2018-04-05 | — | — | US | disclosed |
| US-20180092358-A1 | HERBICIDAL MIXTURES | SYNGENTA PARTICIPATIONS AG (CH) | 2018-04-05 | — | — | US | disclosed |
| US-20180092358-A1 | HERBICIDAL MIXTURES | SYNGENTA PARTICIPATIONS AG (CH) | 2018-04-05 | — | — | US | disclosed |
| EP-3280260-A1 | HERBICIDAL MIXTURES | Syngenta Participations AG (CH) | 2018-02-14 | — | — | EP | disclosed |
| WO-2016162265-A1 | HERBICIDAL MIXTURES | SYNGENTA PARTICIPATIONS AG (CH) | 2016-10-13 | — | — | WO | disclosed |
| WO-2016162265-A1 | HERBICIDAL MIXTURES | SYNGENTA PARTICIPATIONS AG (CH) | 2016-10-13 | — | — | WO | disclosed |
| US-20160264547-A1 | Herbicidal Compounds | SYNGENTA PARTICIPATIONS AG (CH) | 2016-09-15 | — | — | US | disclosed |
| US-20160264547-A1 | Herbicidal Compounds | SYNGENTA PARTICIPATIONS AG (CH) | 2016-09-15 | — | — | US | disclosed |
| US-20160264547-A1 | Herbicidal Compounds | SYNGENTA PARTICIPATIONS AG (CH) | 2016-09-15 | — | — | US | disclosed |
| EP-3054773-A1 | HERBICIDAL COMPOUNDS | Syngenta Participations AG (CH) | 2016-08-17 | — | — | EP | disclosed |
| WO-2015052076-A1 | HERBICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2015-04-16 | — | — | WO | disclosed |
| WO-2015052076-A1 | HERBICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2015-04-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190112288-A1 | HERBICIDAL COMPOUNDS | DDT, RDX, CBR3 | KDR 2800/4885CLK2 3470/4885CLK4 3370/4885 |
| US-20180092358-A1 | HERBICIDAL MIXTURES | DDT, CBR3, AS3MT | KDR 2399/4885CLK2 3148/4885CLK4 2557/4885 |
| US-20160264547-A1 | Herbicidal Compounds | DDT, RDX, CBR3 | KDR 3028/4885CLK2 3581/4885CLK4 3505/4885 |
| US-11608323-B2 | Herbicidal compounds | DDT, RDX, CBR3 | KDR 2800/4885CLK2 3470/4885CLK4 3370/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.