Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | SORT1 | Q99523 | 3/20 | 0.56 |
| ▸ | RIOK2 | Q9BVS4 | 1/20 | 0.54 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.50 |
| ▸ | AR | P10275 | 1/20 | 0.49 |
| ▸ | KDR | P35968 | 1/20 | 0.49 |
| ▸ | CLK2 | P49760 | 1/20 | 0.49 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.49 |
| ▸ | NEK4 | P51957 | 1/20 | 0.49 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.49 |
| ▸ | HIPK4 | Q8NE63 | 1/20 | 0.49 |
| ▸ | SRPK1 | Q96SB4 | 1/20 | 0.49 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.49 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.49 |
| ▸ | MAP3K20 | Q9NYL2 | 1/20 | 0.49 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.49 |
| ▸ | MAP4K5 | Q9Y4K4 | 1/20 | 0.49 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31264157 | 1.00 | ALDH1A1 (0.56) | ALDH1A1GAAL3MBTL1SORT1RIOK2 | |
| SCHEMBL2640650 | 0.91 | NOS3 (0.63) | ALDH1A1GAAL3MBTL1SORT1RIOK2 | |
| SCHEMBL14635931 | 0.87 | KDR (0.49) | ALDH1A1GAAL3MBTL1SORT1RIOK2 | |
| SCHEMBL3192275 | 0.85 | L3MBTL1 (0.55) | ALDH1A1GAAL3MBTL1SORT1RIOK2 | |
| SCHEMBL30875900 | 0.85 | NR3C2 (0.67) | ALDH1A1GAAL3MBTL1SORT1RIOK2 | |
| SCHEMBL5029590 | 0.85 | NR3C2 (0.67) | ALDH1A1GAAL3MBTL1SORT1RIOK2 | |
| SCHEMBL4279750 | 0.83 | SORT1 (0.46) | ALDH1A1GAAL3MBTL1SORT1RIOK2 | |
| SCHEMBL1968503 | 0.83 | ALOX15 (0.60) | SORT1RIOK2GRM5BTKALOX15 | |
| SCHEMBL2635471 | 0.83 | NR3C2 (0.47) | ALDH1A1GAAL3MBTL1SORT1NR3C2 | |
| SCHEMBL23060730 | 0.82 | RIOK2 (0.61) | ALDH1A1GAAL3MBTL1SORT1RIOK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11608323-B2 | Herbicidal compounds | SYNGENTA PARTICIPATIONS AG (CH) | 2023-03-21 | — | — | US | disclosed |
| EP-3054773-B1 | HERBICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2022-01-26 | — | — | EP | disclosed |
| CN-111961033-A | Herbicidal compounds | 先正达参股股份有限公司 | 2020-11-20 | — | — | CN | disclosed |
| EP-3728214-A1 | SUBSTITUTED N-HETEROCYCLYL- AND N-HETEROARYL-TETRAHYDROPYRIMIDINONES AND THE SALTS THEREOF, AND THE USE OF SAME AS HERBICIDAL ACTIVE SUBSTANCES | Bayer Aktiengesellschaft (DE) | 2020-10-28 | — | — | EP | disclosed |
| US-20190112288-A1 | HERBICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2019-04-18 | — | — | US | disclosed |
| US-20160264547-A1 | Herbicidal Compounds | SYNGENTA PARTICIPATIONS AG (CH) | 2016-09-15 | — | — | US | disclosed |
| EP-3054773-A1 | HERBICIDAL COMPOUNDS | Syngenta Participations AG (CH) | 2016-08-17 | — | — | EP | disclosed |
| WO-2015052076-A1 | HERBICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2015-04-16 | — | — | WO | disclosed |
| EP-1957077-B1 | SUBSTITUTED 4-AMINO-PYRROLOTRIAZINE DERIVATIVES USEFUL FOR TREATING HYPER-PROLIFERATIVE DISORDERS AND DISEASES ASSOCIATED WITH ANGIOGENESIS | BAYER HEALTHCARE LLC (US) | 2014-01-22 | — | — | EP | disclosed |
| US-20130225809-A1 | PYRROLOTRIAZINE DERIVATIVES USEFUL FOR TREATING HYPER-PROLIFERATIVE DISORDERS AND DISEASES ASSOCIATED WITH ANGIOGENESIS | BAYER HEALTHCARE LLC (US) | 2013-08-29 | — | — | US | disclosed |
| WO-2007064931-A2 | SUBSTITUTED 4-AMINO-PYRROLOTRIAZINE DERIVATIVES USEFUL FOR TREATING HYPER-PROLIFERATIVE DISORDERS AND DISEASES ASSOCIATED WITH ANGIOGENESIS | BAYER HEALTHCARE LLC (US) | 2007-06-07 | — | — | WO | disclosed |
| EP-1765823-A1 | PYRROLOTRIAZINE DERIVATIVES USEFUL FOR TREATING HYPER-PROLIFERATIVE DISORDERS AND DISEASES ASSOCIATED WITH ANGIOGENESIS | Bayer Pharmaceuticals Corporation (US) | 2007-03-28 | — | — | EP | disclosed |
| CN-1917880-A | Pyrimidines with tie2 (tek) activity | ASTRAZENECA AB (SE) | 2007-02-21 | — | — | CN | disclosed |
| CN-1917879-A | Pyrimidines with tie2 (tek) activity | ASTRAZENECA AB (SE) | 2007-02-21 | — | — | CN | disclosed |
| WO-2007004749-A1 | FUSED HETEROCYCLIC DERIVATIVES AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-01-11 | — | — | WO | disclosed |
| EP-1737463-A1 | PYRIMIDINES WITH TIE2 (TEK) ACTIVITY | AstraZeneca AB (SE) | 2007-01-03 | — | — | EP | disclosed |
| EP-1737462-A1 | PYRIMIDINES WITH TIE2 (TEK) ACTIVITY | AstraZeneca AB (SE) | 2007-01-03 | — | — | EP | disclosed |
| WO-2005121147-A1 | PYRROLOTRIAZINE DERIVATIVES USEFUL FOR TREATING HYPER-PROLIFERATIVE DISORDERS AND DISEASES ASSOCIATED WITH ANGIOGENESIS | BAYER PHARMACEUTICALS CORPORATION (US) | 2005-12-22 | — | — | WO | disclosed |
| WO-2005060970-A1 | PYRIMIDINES WITH TIE2 (TEK) ACTIVITY | ASTRAZENECA AB (SE) | 2005-07-07 | — | — | WO | disclosed |
| WO-2005060969-A1 | PYRIMIDINES WITH TIE2 (TEK) ACTIVITY | ASTRAZENECA AB (SE) | 2005-07-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190112288-A1 | HERBICIDAL COMPOUNDS | DDT, RDX, CBR3 | ALDH1A1 229/4885GAA 1539/4885L3MBTL1 2657/4885 |
| US-20130225809-A1 | PYRROLOTRIAZINE DERIVATIVES USEFUL FOR TREATING HYPER-PROLIFERATIVE DISORDERS AND DISEASES ASSOCIATED WITH ANGIOGENESIS | MKI67, TK2, CDK4 | ALDH1A1 3300/4885GAA 1572/4885L3MBTL1 4182/4885 |
| US-20160264547-A1 | Herbicidal Compounds | DDT, RDX, CBR3 | ALDH1A1 201/4885GAA 1666/4885L3MBTL1 2931/4885 |
| US-11608323-B2 | Herbicidal compounds | DDT, RDX, CBR3 | ALDH1A1 229/4885GAA 1539/4885L3MBTL1 2657/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.