SCHEMBL16637760

SCHEMBL16637760

CCONc1ccc(C)cc1

nearest known ligand 0.46

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.46
HTT P42858 2/20 0.43
GAA P10253 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
DHODH Q02127 1/20 0.42
POLB P06746 2/20 0.40
HPGD P15428 1/20 0.39
RAB9A P51151 1/20 0.39
TDP1 Q9NUW8 2/20 0.38
ACHE P22303 1/20 0.38
MEN1 O00255 1/20 0.38
LMNA P02545 1/20 0.38
KMT2A Q03164 1/20 0.38
ALDH1A1 P00352 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29963693 0.83 TP53 (0.38) MAPTHTTGAASMN1; SMN2POLB
SCHEMBL10442226 0.81 KCNH3 (0.37) MAPTHTTGAASMN1; SMN2POLB
SCHEMBL27944571 0.79 MAPT (0.44) MAPTGAASMN1; SMN2POLBTDP1
SCHEMBL11795587 0.79 ALDH1A1 (0.42) MAPTGAASMN1; SMN2POLBHPGD
SCHEMBL2026345 0.79 TDP1 (0.46) MAPTHTTGAASMN1; SMN2RAB9A
SCHEMBL45188 0.78 KCNH3 (0.49) MAPTGAAHPGDTDP1LMNA
SCHEMBL9091925 0.77 MAPT (0.54) MAPTHTTGAASMN1; SMN2RAB9A
Ethane SCHEMBL11766692 0.76 KCNH3 (0.47) MAPTGAASMN1; SMN2HPGDTDP1
Hydrochloric Acid SCHEMBL28313389 0.76 KCNH3 (0.51) MAPTGAASMN1; SMN2HPGDTDP1
SCHEMBL27328904 0.76 HTT (0.38) MAPTHTTGAASMN1; SMN2POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11597735-B2 Highly efficient free radical photopolymerizations through enabled dark cure THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (US) 2023-03-07 US claimed
US-20210163508-A1 HIGHLY EFFICIENT FREE RADICAL PHOTOPOLYMERIZATIONS THROUGH ENABLED DARK CURE THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE 2021-06-03 US claimed
CN-107722885-B A kind of acrylic bathtub docking adhesive and its application 东莞市科惠工业材料有限公司 2019-08-13 CN claimed
WO-2019113602-A1 HIGHLY EFFICIENT FREE RADICAL PHOTOPOLYMERIZATIONS THROUGH ENABLED DARK CURE THE REGENTS OF THE UNIVERSITY OF COLORADO (US) 2019-06-13 WO claimed
CN-107108894-A Double solidification polythiaethers 3M创新有限公司 2017-08-29 CN claimed
US-11597735-B2 Highly efficient free radical photopolymerizations through enabled dark cure THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (US) 2023-03-07 US disclosed
US-20210163508-A1 HIGHLY EFFICIENT FREE RADICAL PHOTOPOLYMERIZATIONS THROUGH ENABLED DARK CURE THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE 2021-06-03 US disclosed
CN-107722885-B A kind of acrylic bathtub docking adhesive and its application 东莞市科惠工业材料有限公司 2019-08-13 CN disclosed
WO-2019113602-A1 HIGHLY EFFICIENT FREE RADICAL PHOTOPOLYMERIZATIONS THROUGH ENABLED DARK CURE THE REGENTS OF THE UNIVERSITY OF COLORADO (US) 2019-06-13 WO disclosed
CN-105792794-B Dental composition 登特斯普伊德特雷有限公司 2019-03-15 CN disclosed
CN-108314980-A A kind of adhesive and its application method 东莞市科惠工业材料有限公司 2018-07-24 CN disclosed
CN-107722885-A A kind of acrylic bathtub docking adhesive and its application 东莞市科惠工业材料有限公司 2018-02-23 CN disclosed
CN-100335022-C Adhesive compound for tooth KURARAY CO (JP) 2007-09-05 CN disclosed
CN-1226121-C Fiber reinforced plastic mould product, its making method and its shape forming mould DAINIPPON INK & CHEMICALS (JP) 2005-11-09 CN disclosed
CN-1146382-C Dental bottom 可乐丽股份有限公司 2004-04-21 CN disclosed
CN-1378905-A Fiber reinforced plastic mould product, its making method and its shape forming mould DAINIPPON INK & CHEMICALS (JP) 2002-11-13 CN disclosed
CN-1362954-A Sulfamidohydroxamic acid metalloprotease inhibitor SEARLE & CO (US) 2002-08-07 CN disclosed
CN-1270016-A Dental bottom KURARAY CO (JP) 2000-10-18 CN disclosed
CN-1253767-A Adhesive compound for tooth KURARAY CO (JP) 2000-05-24 CN disclosed
CN-1004485-B Method for producing -acrylic acid esters 拜尔公司 1989-06-14 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11597735-B2 Highly efficient free radical photopolymerizations through enabled dark cure PHF2, KDM3B, KDM2B MAPT 4310/4885HTT 2243/4885GAA 3272/4885
US-20210163508-A1 HIGHLY EFFICIENT FREE RADICAL PHOTOPOLYMERIZATIONS THROUGH ENABLED DARK CURE PHF2, KDM3B, KDM2B MAPT 4310/4885HTT 2243/4885GAA 3272/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.