Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.54 |
| ▸ | GAA | P10253 | 5/20 | 0.54 |
| ▸ | NPC1 | O15118 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | THRB | P10828 | 1/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | CA1 | P00915 | 2/20 | 0.48 |
| ▸ | CA2 | P00918 | 2/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA7 | P43166 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.48 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21322050 | 0.83 | GAA (0.50) | MAPTGAANPC1KDM4ERAB9A | |
| SCHEMBL10442226 | 0.82 | KCNH3 (0.37) | MAPTGAANPC1KDM4ERAB9A | |
| SCHEMBL29963693 | 0.79 | TP53 (0.38) | MAPTGAANPC1KDM4ERAB9A | |
| SCHEMBL6852891 | 0.79 | GAA (0.50) | MAPTGAANPC1KDM4ERAB9A | |
| SCHEMBL11510051 | 0.79 | KDM4E (0.49) | MAPTGAANPC1KDM4ERAB9A | |
| SCHEMBL5554561 | 0.78 | LTA4H (0.57) | MAPTGAANPC1RAB9AL3MBTL1 | |
| SCHEMBL16637760 | 0.77 | MAPT (0.46) | MAPTGAARAB9ATDP1SMN1; SMN2 | |
| SCHEMBL812574 | 0.77 | RAB9A (0.64) | MAPTGAANPC1KDM4ERAB9A | |
| SCHEMBL10436614 | 0.76 | ALDH1A1 (0.53) | MAPTNPC1RAB9AMAPK1SMN1; SMN2 | |
| SCHEMBL9096011 | 0.76 | GAA (0.52) | MAPTGAANPC1KDM4ERAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5541299-A | Process for the preparation of dyestuffs | BAYER AKTIENGESELLSCHAFT (DE) | 1996-07-30 | — | — | US | disclosed |
| EP-0446731-B1 | Process for the manufacture of azo dyes | BAYER AG (DE) | 1995-05-03 | — | — | EP | disclosed |
| EP-0446731-A2 | Process for the manufacture of azo dyes | BAYER AG (DE) | 1991-09-18 | — | — | EP | disclosed |