Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDXK | O00764 | 1/20 | 0.38 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 3/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | KCNQ3 | O43525 | 2/20 | 0.34 |
| ▸ | KCNQ2 | O43526 | 2/20 | 0.34 |
| ▸ | KCNE1 | P15382 | 2/20 | 0.34 |
| ▸ | KCNQ1 | P51787 | 2/20 | 0.34 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.34 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.33 |
| ▸ | JUN | P05412 | 2/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.33 |
| ▸ | RELA | Q04206 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17979054 | 0.85 | RECQL (0.36) | PDXKPIK3R1PIK3CANOTUMRECQL | |
| SCHEMBL30031898 | 0.85 | RECQL (0.36) | PDXKPIK3R1PIK3CANOTUMRECQL | |
| SCHEMBL18367360 | 0.82 | AR (0.35) | PDXKRECQLALDH1A1GAAHTT | |
| SCHEMBL20457490 | 0.81 | AKR1C3 (0.39) | PIK3R1PIK3CAGAAKCNQ3KCNQ2 | |
| SCHEMBL16647335 | 0.79 | KDM4E (0.39) | PDXKNOTUMALDH1A1P2RX7NR1H2 | |
| SCHEMBL21598903 | 0.77 | PIK3R1 (0.37) | PIK3R1PIK3CAKCNQ3KCNQ2KCNE1 | |
| SCHEMBL16637276 | 0.77 | TRPA1 (0.39) | PIK3R1PIK3CAHTTAKR1C3AKR1C2 | |
| SCHEMBL29416192 | 0.76 | PDXK (0.45) | PDXKRECQLALDH1A1MAPT | |
| SCHEMBL3840400 | 0.76 | PIK3R1 (0.42) | PIK3R1PIK3CANOTUMALDH1A1HTT | |
| SCHEMBL903476 | 0.76 | PDXK (0.45) | PDXKRECQLALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240327390-A1 | SUBSTITUTED NITROGEN CONTAINING COMPOUNDS | BRISTOL MYERS SQUIBB CO (US) | 2024-10-03 | — | — | US | disclosed |
| EP-3929194-B1 | SUBSTITUTED NITROGEN CONTAINING COMPOUNDS | BRISTOL MYERS SQUIBB CO (US) | 2024-04-17 | — | — | EP | disclosed |
| US-RE49700-E1 | Substituted nitrogen containing compounds | BRISTOL-MYERS SQUIBB COMPANY (US) | 2023-10-17 | — | — | US | disclosed |
| US-RE49700-E1 | Substituted nitrogen containing compounds | BRISTOL-MYERS SQUIBB COMPANY (US) | 2023-10-17 | — | — | US | disclosed |
| US-RE49700-E1 | Substituted nitrogen containing compounds | BRISTOL-MYERS SQUIBB COMPANY (US) | 2023-10-17 | — | — | US | disclosed |
| US-20230303570-A1 | KINASE INHIBITORS AND USES THEREOF | ABM THERAPEUTICS CORP (US) | 2023-09-28 | — | — | US | disclosed |
| US-20230303570-A1 | KINASE INHIBITORS AND USES THEREOF | ABM THERAPEUTICS CORP (US) | 2023-09-28 | — | — | US | disclosed |
| US-20230303570-A1 | KINASE INHIBITORS AND USES THEREOF | ABM THERAPEUTICS CORP (US) | 2023-09-28 | — | — | US | disclosed |
| CN-116710453-A | Kinase inhibitors and uses thereof | 璧辰医药技术股份有限公司 | 2023-09-05 | — | — | CN | disclosed |
| EP-4192582-A1 | KINASE INHIBITORS AND USES THEREOF | ABM Therapeutics Corporation (US) | 2023-06-14 | — | — | EP | disclosed |
| US-20160264547-A1 | Herbicidal Compounds | SYNGENTA PARTICIPATIONS AG (CH) | 2016-09-15 | — | — | US | disclosed |
| US-20160251332-A1 | Herbicidal Compounds | SYNGENTA PARTICIPATIONS AG (CH) | 2016-09-01 | — | — | US | disclosed |
| US-20160251332-A1 | Herbicidal Compounds | SYNGENTA PARTICIPATIONS AG (CH) | 2016-09-01 | — | — | US | disclosed |
| US-20160251332-A1 | Herbicidal Compounds | SYNGENTA PARTICIPATIONS AG (CH) | 2016-09-01 | — | — | US | disclosed |
| EP-3060558-A1 | PYRIDINYLIMIDAZOLONES AS HERBICIDES | Syngenta Participations AG (CH) | 2016-08-31 | — | — | EP | disclosed |
| EP-3054773-A1 | HERBICIDAL COMPOUNDS | Syngenta Participations AG (CH) | 2016-08-17 | — | — | EP | disclosed |
| WO-2015059262-A1 | PYRIDINYLIMIDAZOLONES AS HERBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2015-04-30 | — | — | WO | disclosed |
| WO-2015059262-A1 | PYRIDINYLIMIDAZOLONES AS HERBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2015-04-30 | — | — | WO | disclosed |
| WO-2015052076-A1 | HERBICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2015-04-16 | — | — | WO | disclosed |
| WO-2015052076-A1 | HERBICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2015-04-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230303570-A1 | KINASE INHIBITORS AND USES THEREOF | ERBB2, ERBB3, ERBB4 | PDXK 287/4885PIK3R1 574/4885PIK3CA 114/4885 |
| US-20240327390-A1 | SUBSTITUTED NITROGEN CONTAINING COMPOUNDS | NR0B1, GRK1, GRIN1 | PDXK 1154/4885PIK3R1 2601/4885PIK3CA 2667/4885 |
| US-20160251332-A1 | Herbicidal Compounds | RDX, CBR3, DDT | PDXK 523/4885PIK3R1 2982/4885PIK3CA 4154/4885 |
| US-20160264547-A1 | Herbicidal Compounds | DDT, RDX, CBR3 | PDXK 137/4885PIK3R1 1531/4885PIK3CA 3002/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.