SCHEMBL16638211

SCHEMBL16638211

COc1ccc(-c2cc3ccccc3n2S(=O)(=O)c2ccccc2)c(OC)c1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR6 P50406 3/20 0.51
POLB P06746 2/20 0.51
L3MBTL1 Q9Y468 1/20 0.51
CA12 O43570 3/20 0.50
CA9 Q16790 3/20 0.50
CA2 P00918 1/20 0.50
MEN1 O00255 2/20 0.48
KMT2A Q03164 2/20 0.48
ALDH1A1 P00352 2/20 0.44
HTT P42858 1/20 0.44
CREBBP Q92793 1/20 0.44
CXCL8 P10145 1/20 0.44
NOD1 Q9Y239 1/20 0.44
ACLY P53396 1/20 0.43
TP53 P04637 1/20 0.42
KDM4E B2RXH2 1/20 0.42
PDE4A P27815 2/20 0.42
PDE4B Q07343 2/20 0.42
PDE4C Q08493 2/20 0.42
PDE4D Q08499 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7061811 0.85 HTR6 (0.48) HTR6POLBL3MBTL1CA12CA9
SCHEMBL3686412 0.81 CA12 (0.50) HTR6POLBL3MBTL1CA12CA9
SCHEMBL6860540 0.80 HTR6 (0.50) HTR6POLBL3MBTL1MEN1KMT2A
SCHEMBL2741700 0.78 MEN1 (0.51) HTR6POLBL3MBTL1CA12CA9
SCHEMBL3561484 0.78 ACLY (0.65) HTR6POLBL3MBTL1CA12CA9
SCHEMBL7066962 0.77 HDAC3 (0.54) HTR6POLBL3MBTL1MEN1KMT2A
SCHEMBL7154389 0.77 KMT2A (0.51) L3MBTL1MEN1KMT2AALDH1A1HTT
SCHEMBL225970 0.77 MEN1 (0.49) HTR6POLBL3MBTL1CA12CA9
SCHEMBL25455028 0.76 CA12 (0.56) HTR6POLBL3MBTL1CA12CA9
SCHEMBL7063612 0.75 HDAC3 (0.54) HTR6POLBL3MBTL1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9006463-B2 Slow release of organoboronic acids in cross-coupling reactions THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 2015-04-14 US disclosed