SCHEMBL16638226

SCHEMBL16638226

CCCC(C)(C)c1cc(Oc2cc(C#N)c(C#N)cc2Cl)c(C(C)(C)CCC)cc1OC

nearest known ligand 0.36

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
AR P10275 10/20 0.36
NR3C1 P04150 4/20 0.34
NR3C2 P08235 4/20 0.34
PGR P06401 2/20 0.34
SRC P12931 3/20 0.33
ALDH1A1 P00352 2/20 0.33
KDM4E B2RXH2 1/20 0.33
USP2 O75604 1/20 0.33
GAA P10253 1/20 0.32
MAPT P10636 1/20 0.32
HPGD P15428 1/20 0.32
ABL1 P00519 1/20 0.32
BCR P11274 1/20 0.32
SLC6A4 P31645 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16638227 0.91 AR (0.40) ARNR3C1NR3C2PGRALDH1A1
SCHEMBL16638230 0.85 AR (0.40) ARNR3C1NR3C2PGR
SCHEMBL16638555 0.76 TP53 (0.44) NR3C1NR3C2KDM4EMAPTHPGD
SCHEMBL16638223 0.72 LMNA (0.38) HPGD
SCHEMBL28427625 0.71 SMN1; SMN2 (0.51) ARALDH1A1KDM4EUSP2GAA
SCHEMBL21302122 0.70 ALDH1A1 (0.37) NR3C1NR3C2PGRALDH1A1KDM4E
SCHEMBL25968794 0.69 AR (0.42) ARNR3C1NR3C2PGRSLC6A4
SCHEMBL31542099 0.68 ALOX15 (0.58) ARALDH1A1KDM4EMAPTHPGD
SCHEMBL8749333 0.68 ALOX15 (0.58) ARALDH1A1KDM4EMAPTHPGD
SCHEMBL11259141 0.68 LMNA (0.37) HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9006428-B2 High transmissional green dye for LCD and synthetic method thereof LG DISPLAY CO., LTD. (KR) 2015-04-14 US disclosed
US-9006428-B2 High transmissional green dye for LCD and synthetic method thereof LG DISPLAY CO., LTD. (KR) 2015-04-14 US disclosed