Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOD1 | Q9Y239 | 8/20 | 0.53 |
| ▸ | GLP1R | P43220 | 8/20 | 0.50 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.48 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.48 |
| ▸ | FNTA | P49354 | 2/20 | 0.45 |
| ▸ | FNTB | P49356 | 2/20 | 0.45 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16638258 | 1.00 | NOD1 (0.53) | NOD1GLP1RITGB3ITGA2BFNTA | |
| SCHEMBL16638272 | 1.00 | NOD1 (0.53) | NOD1GLP1RITGB3ITGA2BFNTA | |
| SCHEMBL16638315 | 0.97 | NOD1 (0.56) | NOD1GLP1RITGB3ITGA2B | |
| SCHEMBL24776211 | 0.92 | NOD1 (0.50) | NOD1GLP1RITGB3ITGA2BFNTA | |
| SCHEMBL7002282 | 0.91 | NOD1 (0.48) | NOD1GLP1RITGB3ITGA2BFNTA | |
| SCHEMBL12993536 | 0.90 | NOD1 (0.53) | NOD1GLP1RITGB3ITGA2B | |
| SCHEMBL12499995 | 0.90 | ITGB3 (0.54) | NOD1GLP1RITGB3ITGA2B | |
| SCHEMBL15975845 | 0.90 | ITGB3 (0.54) | NOD1GLP1RITGB3ITGA2B | |
| SCHEMBL16699151 | 0.90 | NOD1 (0.45) | NOD1GLP1RITGB3ITGA2BFNTA | |
| SCHEMBL4539085 | 0.90 | NOD1 (0.45) | NOD1GLP1RITGB3ITGA2BFNTA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9006178-B2 | Double-acylated GLP-1 derivatives with a linker | NOVO NORDISK A/S (DK) | 2015-04-14 | — | — | US | disclosed |