Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | AKT1 | P31749 | 1/20 | 0.43 |
| ▸ | NAAA | Q02083 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | CTSL | P07711 | 1/20 | 0.39 |
| ▸ | CTSB | P07858 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.39 |
| ▸ | CDC25B | P30305 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3698177 | 1.00 | LMNA (0.47) | LMNAAKT1NAAATSHRBCHE | |
| SCHEMBL14028840 | 1.00 | LMNA (0.47) | LMNAAKT1NAAATSHRBCHE | |
| SCHEMBL2610008 | 0.91 | LMNA (0.54) | LMNAAKT1NAAATSHRBCHE | |
| SCHEMBL2181334 | 0.91 | LMNA (0.54) | LMNAAKT1NAAATSHRBCHE | |
| SCHEMBL14667678 | 0.86 | LMNA (0.48) | LMNAAKT1NAAATSHRBCHE | |
| SCHEMBL12537283 | 0.80 | LMNA (0.50) | LMNAAKT1NAAATSHRBCHE | |
| SCHEMBL4347938 | 0.79 | CTRB1 (0.44) | — | |
| SCHEMBL461037 | 0.79 | CTRB1 (0.44) | — | |
| SCHEMBL23773045 | 0.76 | LMNA (0.47) | LMNAAKT1NAAATSHRBCHE | |
| SCHEMBL567091 | 0.75 | LMNA (0.49) | LMNAAKT1TSHRBCHEACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160022835-A1 | Targeted Polymeric Inflammation-Resolving Nanoparticles | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2016-01-28 | — | — | US | disclosed |
| US-20160022835-A1 | Targeted Polymeric Inflammation-Resolving Nanoparticles | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2016-01-28 | — | — | US | disclosed |
| US-9006349-B2 | Temperature-sensitive polyethylene glycol / polyester block copolymer in which bioactive functional group is introduced into side chain thereof | AJOU UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION (KR) | 2015-04-14 | — | — | US | disclosed |
| US-9006349-B2 | Temperature-sensitive polyethylene glycol / polyester block copolymer in which bioactive functional group is introduced into side chain thereof | AJOU UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION (KR) | 2015-04-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160022835-A1 | Targeted Polymeric Inflammation-Resolving Nanoparticles | MRGPRX1, MRGPRX2, CXCL10 | LMNA 1612/4885AKT1 1712/4885NAAA 2111/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.