Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | PAOX | Q6QHF9 | 2/20 | 0.34 |
| ▸ | ICMT | O60725 | 1/20 | 0.33 |
| ▸ | ALB | P02768 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.32 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.31 |
| ▸ | KDM7A | Q6ZMT4 | 1/20 | 0.30 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.30 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16638618 | 1.00 | LMNA (0.41) | LMNAALDH1A1PAOXICMTALB | |
| SCHEMBL12791503 | 0.91 | LMNA (0.48) | LMNAALDH1A1ICMTALBPOLB | |
| SCHEMBL12791476 | 0.91 | LMNA (0.48) | LMNAALDH1A1ICMTALBPOLB | |
| SCHEMBL16638616 | 0.91 | PAOX (0.40) | LMNAALDH1A1PAOX | |
| SCHEMBL16638622 | 0.88 | PAOX (0.38) | LMNAPAOX | |
| SCHEMBL16638635 | 0.87 | PAOX (0.40) | LMNAALDH1A1PAOX | |
| SCHEMBL16638632 | 0.86 | PAOX (0.37) | LMNAPAOX | |
| SCHEMBL16638633 | 0.85 | PAOX (0.39) | LMNAALDH1A1PAOX | |
| SCHEMBL17433024 | 0.85 | PAOX (0.40) | LMNAPAOXICMTALB | |
| SCHEMBL17433013 | 0.85 | TERT (0.35) | LMNAPAOXICMTALB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9006487-B2 | Amine-containing lipids and uses thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2015-04-14 | — | — | US | disclosed |