Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TERT | O14746 | 1/20 | 0.35 |
| ▸ | ICMT | O60725 | 1/20 | 0.32 |
| ▸ | ALB | P02768 | 1/20 | 0.32 |
| ▸ | PAOX | Q6QHF9 | 3/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.30 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.30 |
| ▸ | ITGAL | P20701 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12791551 | 0.87 | LMNA (0.40) | ICMTALBLMNA | |
| SCHEMBL12791475 | 0.85 | LMNA (0.41) | ICMTALBLMNA | |
| SCHEMBL16638647 | 0.85 | LMNA (0.41) | ICMTALBPAOXLMNA | |
| SCHEMBL16638618 | 0.85 | LMNA (0.41) | ICMTALBPAOXLMNA | |
| SCHEMBL16504265 | 0.83 | TERT (0.43) | TERTICMTALBLMNAITGB2 | |
| SCHEMBL12791153 | 0.83 | TERT (0.43) | TERTICMTALBLMNAITGB2 | |
| SCHEMBL16638623 | 0.82 | PAOX (0.38) | TERTICMTALBPAOXLMNA | |
| SCHEMBL12791820 | 0.78 | LMNA (0.36) | LMNA | |
| SCHEMBL17433024 | 0.78 | PAOX (0.40) | ICMTALBPAOXLMNA | |
| SCHEMBL15870003 | 0.77 | ALDH1A1 (0.45) | TERTICMTALBPAOXLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160009657-A1 | AMINE-CONTAINING LIPIDS AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2016-01-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160009657-A1 | AMINE-CONTAINING LIPIDS AND USES THEREOF | PHOSPHO1, CHMP4B, SGMS1 | TERT 1952/4885ICMT 506/4885ALB 891/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.