Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.44 |
| ▸ | HTT | P42858 | 3/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | PIK3C2B | O00750 | 1/20 | 0.41 |
| ▸ | PIK3C2G | O75747 | 1/20 | 0.41 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.40 |
| ▸ | TUBB | P07437 | 1/20 | 0.40 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.40 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.40 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.40 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.40 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.40 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8835541 | 0.87 | GRM4 (0.50) | MEN1KMT2AHTTNPC1ALDH1A1 | |
| SCHEMBL9402386 | 0.83 | MEN1 (0.63) | MEN1KMT2AHTTPKMMAPK1 | |
| SCHEMBL8835483 | 0.81 | RAB9A (0.60) | MEN1KMT2AHTTMAPK1NPC1 | |
| SCHEMBL15636276 | 0.79 | MEN1 (0.72) | MEN1KMT2AHTTPKMMAPK1 | |
| SCHEMBL17363143 | 0.79 | MEN1 (0.58) | MEN1KMT2AHTTPKMMAPK1 | |
| SCHEMBL16638716 | 0.79 | MEN1 (0.58) | MEN1KMT2AHTTPKMMAPK1 | |
| SCHEMBL6643061 | 0.79 | NPC1 (0.59) | MEN1KMT2AHTTNPC1ALDH1A1 | |
| SCHEMBL10680055 | 0.78 | TEK (0.50) | ALDH1A1RAB9ATUBB1GAAEGFR | |
| SCHEMBL16638713 | 0.78 | GRM4 (0.58) | MEN1KMT2ANPC1ALDH1A1RAB9A | |
| SCHEMBL9402383 | 0.77 | RAB9A (0.57) | MEN1KMT2AHTTNPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9006451-B1 | 2-anilinonicotinyl based chalcones useful as potential anticancer agents and process for preparation thereof | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2015-04-14 | — | — | US | disclosed |