Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM4 | Q14833 | 3/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | EGFR | P00533 | 1/20 | 0.45 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.45 |
| ▸ | BCL6 | P41182 | 2/20 | 0.45 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.44 |
| ▸ | PIP4K2A | P48426 | 1/20 | 0.44 |
| ▸ | MALT1 | Q9UDY8 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10680055 | 0.81 | TEK (0.50) | GAARAB9AEGFRALDH1A1 | |
| SCHEMBL16638714 | 0.79 | GRM4 (0.59) | GRM4KMT2AMEN1MAPTGAA | |
| SCHEMBL15635904 | 0.79 | RAB9A (0.65) | GRM4KMT2AMEN1MAPTNPC1 | |
| SCHEMBL15635675 | 0.79 | GRM4 (0.57) | GRM4KMT2AMEN1MAPTGAA | |
| SCHEMBL8835483 | 0.79 | RAB9A (0.60) | KMT2AMEN1MAPTGAANPC1 | |
| SCHEMBL9402386 | 0.78 | MEN1 (0.63) | GRM4KMT2AMEN1MAPTNPC1 | |
| SCHEMBL16638715 | 0.78 | MEN1 (0.44) | GRM4KMT2AMEN1MAPTGAA | |
| SCHEMBL9402383 | 0.77 | RAB9A (0.57) | KMT2AMEN1MAPTNPC1RAB9A | |
| SCHEMBL6643061 | 0.76 | NPC1 (0.59) | GRM4KMT2AMEN1MAPTNPC1 | |
| SCHEMBL8835541 | 0.76 | GRM4 (0.50) | GRM4KMT2AMEN1MAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9006451-B1 | 2-anilinonicotinyl based chalcones useful as potential anticancer agents and process for preparation thereof | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2015-04-14 | — | — | US | disclosed |