Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16638908 | 0.91 | OPRK1 (0.35) | OPRK1 | |
| SCHEMBL16638930 | 0.90 | OPRK1 (0.37) | OPRK1 | |
| SCHEMBL10239898 | 0.88 | OPRK1 (0.43) | OPRK1 | |
| SCHEMBL16638906 | 0.88 | OPRK1 (0.43) | OPRK1 | |
| SCHEMBL2618744 | 0.83 | OPRK1 (0.35) | OPRK1 | |
| SCHEMBL16638911 | 0.80 | HCRTR1 (0.50) | — | |
| SCHEMBL10239895 | 0.78 | OPRK1 (0.33) | OPRK1 | |
| SCHEMBL2610410 | 0.78 | CYP3A4 (0.37) | OPRK1 | |
| SCHEMBL2618510 | 0.77 | SIGMAR1 (0.34) | OPRK1 | |
| SCHEMBL16638949 | 0.77 | SLC6A2 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2626350-B1 | CYCLOPROPANE COMPOUND | EISAI R&D MAN CO LTD (JP) | 2015-04-15 | — | — | EP | disclosed |