Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | CCR2 | P41597 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 2/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.32 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16638921 | 0.89 | SLC6A2 (0.31) | SLC6A2 | |
| SCHEMBL10239906 | 0.89 | SLC6A2 (0.31) | SLC6A2 | |
| SCHEMBL16638908 | 0.83 | OPRK1 (0.35) | SLC6A2SLC6A4CCR2HTR2AHTR2C | |
| SCHEMBL2118280 | 0.78 | HTR2A (0.36) | SLC6A2SLC6A4CCR2HTR2AHTR2C | |
| SCHEMBL16638910 | 0.77 | OPRK1 (0.34) | — | |
| SCHEMBL16638930 | 0.73 | OPRK1 (0.37) | HSD11B1 | |
| SCHEMBL10239898 | 0.73 | OPRK1 (0.43) | SLC6A2 | |
| SCHEMBL16638906 | 0.73 | OPRK1 (0.43) | SLC6A2 | |
| SCHEMBL2618744 | 0.71 | OPRK1 (0.35) | — | |
| SCHEMBL16638950 | 0.71 | HCRTR1 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2626350-B1 | CYCLOPROPANE COMPOUND | EISAI R&D MAN CO LTD (JP) | 2015-04-15 | — | — | EP | disclosed |