Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 17/20 | 0.40 |
| ▸ | HCRTR2 | O43614 | 17/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.40 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.31 |
| ▸ | IL6 | P05231 | 1/20 | 0.31 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15161952 | 0.83 | HCRTR1 (0.40) | HCRTR1HCRTR2KCNH2 | |
| SCHEMBL16638908 | 0.80 | OPRK1 (0.35) | — | |
| SCHEMBL16638911 | 0.78 | HCRTR1 (0.50) | HCRTR1HCRTR2KCNH2 | |
| SCHEMBL2619022 | 0.76 | — | — | |
| SCHEMBL16638907 | 0.75 | HCRTR1 (0.49) | HCRTR1HCRTR2KCNH2 | |
| SCHEMBL2618745 | 0.75 | HCRTR1 (0.43) | HCRTR1HCRTR2KCNH2 | |
| SCHEMBL15161953 | 0.74 | HCRTR1 (0.39) | HCRTR1HCRTR2KCNH2 | |
| SCHEMBL16638910 | 0.72 | OPRK1 (0.34) | — | |
| SCHEMBL16638949 | 0.71 | SLC6A2 (0.34) | — | |
| SCHEMBL2610685 | 0.70 | HCRTR1 (0.73) | HCRTR1HCRTR2KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2626350-B1 | CYCLOPROPANE COMPOUND | EISAI R&D MAN CO LTD (JP) | 2015-04-15 | — | — | EP | disclosed |