SCHEMBL16638968

SCHEMBL16638968

NC(O)c1cccc(O)c1O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.50
HPGD P15428 3/20 0.50
CA1 P00915 2/20 0.50
CA2 P00918 2/20 0.50
ALDH1A1 P00352 2/20 0.50
ALOX15 P16050 2/20 0.50
HSD17B10 Q99714 2/20 0.50
ADAMTS4 O75173 1/20 0.50
EGFR P00533 1/20 0.50
FYN P06241 1/20 0.50
MMP2 P08253 1/20 0.50
MMP9 P14780 1/20 0.50
MMP8 P22894 1/20 0.50
CA6 P23280 1/20 0.50
CDK2 P24941 1/20 0.50
MMP12 P39900 1/20 0.50
RECQL P46063 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
ADAMTS5 Q9UNA0 1/20 0.50
DBH P09172 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL640127 0.80 GABRA1 (0.54) LMNAHPGDCA1CA2ALDH1A1
SCHEMBL8582907 0.80 LMNA (0.55) LMNAHPGDCA1CA2ALDH1A1
SCHEMBL135746 0.79 LMNA (0.50) LMNAHPGDCA1CA2ALDH1A1
Bromide SCHEMBL209321 0.78 GABRA1 (0.52) LMNAHPGDCA1CA2ALDH1A1
SCHEMBL11043623 0.77 ADRA2A (0.55) LMNAHPGDCA1CA2ALDH1A1
SCHEMBL4334723 0.77 ADRA2A (0.55) LMNAHPGDCA1CA2ALDH1A1
SCHEMBL1421008 0.76 HPGD (0.52) LMNAHPGDCA1CA2ALDH1A1
SCHEMBL31618862 0.76 HPGD (0.52) LMNAHPGDCA1CA2ALDH1A1
SCHEMBL960309 0.76 LMNA (0.44) LMNAHPGDCA1CA2ALDH1A1
SCHEMBL3054160 0.76 LMNA (0.44) LMNAHPGDCA1CA2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108947546-B Refractory material binder and preparation method and application thereof 浙江自立高分子化工材料有限公司 2021-09-07 CN disclosed
EP-2114905-B1 MULTI-COLOR TIME RESOLVED FLUOROPHORES BASED ON MACROCYCLIC LANTHANIDE COMPLEXES LUMIPHORE INC (US) 2015-04-15 EP disclosed