Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4Z1 | Q86W10 | 10/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | THPO | P40225 | 1/20 | 0.55 |
| ▸ | SLC9A1 | P19634 | 4/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.50 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.46 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.45 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.45 |
| ▸ | CYP4F8 | P98187 | 1/20 | 0.45 |
| ▸ | CYP4F12 | Q9HCS2 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18833167 | 0.79 | CYP4Z1 (0.53) | CYP4Z1CYP1A2MAPTALDH1A1CYP3A4 | |
| SCHEMBL5662069 | 0.79 | CYP4Z1 (0.57) | CYP4Z1CYP1A2MAPTALDH1A1CYP3A4 | |
| SCHEMBL7243835 | 0.79 | POLB (0.55) | CYP4Z1CYP1A2MAPTALDH1A1CYP3A4 | |
| SCHEMBL29518725 | 0.79 | CYP4Z1 (0.57) | CYP4Z1CYP1A2MAPTALDH1A1CYP3A4 | |
| SCHEMBL8491002 | 0.76 | CYP4Z1 (0.50) | CYP4Z1CYP1A2MAPTALDH1A1CYP3A4 | |
| SCHEMBL1757405 | 0.76 | CYP4Z1 (0.50) | CYP4Z1CYP1A2MAPTALDH1A1CYP3A4 | |
| SCHEMBL2748 | 0.76 | CYP4Z1 (0.50) | CYP4Z1CYP1A2MAPTALDH1A1CYP3A4 | |
| SCHEMBL5027960 | 0.75 | CYP4Z1 (0.49) | CYP4Z1CYP1A2MAPTALDH1A1CYP3A4 | |
| SCHEMBL14679890 | 0.75 | CYP4Z1 (0.71) | CYP4Z1CYP1A2MAPTALDH1A1CYP3A4 | |
| SCHEMBL19502450 | 0.75 | CYP4Z1 (0.53) | CYP4Z1CYP1A2MAPTALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2190839-B1 | A PROCESS FOR CHIRAL RESOLUTION OF 2-SUBSTITUTED 4-SUBSTITUTED 1,3-OXATHIOLANES | AVEXA LTD (AU) | 2015-04-15 | — | — | EP | disclosed |