SCHEMBL5662069

SCHEMBL5662069

CNn1nnc2ccccc21

nearest known ligand 0.57

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CYP4Z1 Q86W10 10/20 0.57
SLC9A1 P19634 5/20 0.55
KEAP1 Q14145 1/20 0.55
CYP1A2 P05177 2/20 0.50
POLB P06746 1/20 0.50
MAPK1 P28482 1/20 0.50
ATM Q13315 1/20 0.50
ALDH1A1 P00352 1/20 0.50
CYP3A4 P08684 1/20 0.50
CYP2D6 P10635 1/20 0.50
MAPT P10636 1/20 0.50
CYP2C9 P11712 1/20 0.50
THPO P40225 1/20 0.50
DGAT1 O75907 1/20 0.46
CYP2C8 P10632 1/20 0.45
CYP2B6 P20813 1/20 0.45
CYP4F8 P98187 1/20 0.45
CYP4F12 Q9HCS2 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29518725 1.00 CYP4Z1 (0.57) CYP4Z1SLC9A1KEAP1CYP1A2POLB
SCHEMBL18833167 0.79 CYP4Z1 (0.53) CYP4Z1SLC9A1KEAP1CYP1A2POLB
SCHEMBL7243835 0.79 POLB (0.55) CYP4Z1SLC9A1KEAP1CYP1A2POLB
SCHEMBL16639135 0.79 CYP4Z1 (0.55) CYP4Z1SLC9A1KEAP1CYP1A2POLB
SCHEMBL19502450 0.79 CYP4Z1 (0.53) CYP4Z1SLC9A1KEAP1CYP1A2POLB
SCHEMBL14679890 0.79 CYP4Z1 (0.71) CYP4Z1SLC9A1KEAP1CYP1A2POLB
SCHEMBL8491002 0.76 CYP4Z1 (0.50) CYP4Z1SLC9A1KEAP1CYP1A2POLB
SCHEMBL238589 0.76 CYP4Z1 (0.50) CYP4Z1SLC9A1KEAP1CYP1A2POLB
SCHEMBL19896954 0.75 KCNMA1 (0.42) CYP4Z1CYP1A2POLBALDH1A1MAPT
SCHEMBL10434384 0.75 ALDH1A1 (0.49) CYP4Z1ATMALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107614754-B The manufacturing method of the evaporator of refrigerating plant 大金工业株式会社 2018-12-21 CN claimed
WO-2015052558-A1 COMPRESSOR OIL, AND COMPRESSOR OIL ADDITIVE COMPOSITION INDIAN OIL CORPORATION LIMITED (IN) 2015-04-16 WO claimed
EP-2794820-A1 ADDITIVE COMPOSITIONS THAT IMPROVE THE LACQUERING RESISTANCE OF SUPERIOR QUALITY DIESEL OR BIODIESEL FUELS Total Raffinage & Marketing (FR) 2014-10-29 EP claimed
WO-2013092533-A1 ADDITIVE COMPOSITIONS THAT IMPROVE THE LACQUERING RESISTANCE OF SUPERIOR QUALITY DIESEL OR BIODIESEL FUELS TOTAL RAFFINAGE MARKETING (FR) 2013-06-27 WO claimed
EP-1749302-A2 METHOD AND APPARATUS FOR ADMINISTERING PASSIVATOR TO A CONDUCTOR ABB Technology Ltd (CH) 2007-02-07 EP claimed
WO-2005117031-A2 METHOD AND APPARATUS FOR ADMINISTERING PASSIVATOR TO A CONDUCTOR ABB TECHNOLOGY LTD. (US) 2005-12-08 WO claimed
US-11319303-B2 Compound used as autophagy regulator, and preparation method therefor and uses thereof Wigen Biomedicine Technology (shanghai) Co., Ltd. (CN) 2022-05-03 US disclosed
US-11274849-B2 Smart thermostat with model predictive control and demand response integration Johnson Controls Tyco IP Holdings LLP (US) 2022-03-15 US disclosed
CN-113448167-A Photosensitive resin composition 味之素株式会社 2021-09-28 CN disclosed
EP-3476924-B1 GREASE FOR REFRIGERATING MACHINE OIL MITSUBISHI HEAVY IND THERMAL SYSTEMS LTD (JP) 2021-05-12 EP disclosed
US-20200190066-A1 COMPOUND USED AS AUTOPHAGY REGULATOR, AND PREPARATION METHOD THEREFOR AND USES THEREOF Wigen Biomedicine Technology (shanghai) Co., Ltd. (CN) 2020-06-18 US disclosed
US-20200069609-A1 METHOD FOR COVALENT BOND MODIFYING MAMMALIAN ATG8 HOMOLOGUE Wigen Biomedicine Technology (shanghai) Co., Ltd. (CN) 2020-03-05 US disclosed
CN-106133123-B Lubricant oil composite 捷客斯能源株式会社 2019-11-19 CN disclosed
CN-107922869-A To contain organic molybdenum and the additive of the lubricant compositions of derivatization triazole 范德比尔特化学品有限责任公司 2018-04-17 CN disclosed
CN-103717716-B Lubricant for refrigeration compressor 艾默生环境优化技术有限公司 2017-04-12 CN disclosed
CN-104403741-B A kind of worm and gear lubricant oil composite and preparation method thereof 中国石油化工股份有限公司 2017-03-29 CN disclosed
US-9175058-B2 Soluble immune response suppressor polypeptides and treatment of multiple sclerosis and other autoimmune diseases THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) 2015-11-03 US disclosed
WO-2015052558-A1 COMPRESSOR OIL, AND COMPRESSOR OIL ADDITIVE COMPOSITION INDIAN OIL CORPORATION LIMITED (IN) 2015-04-16 WO disclosed
US-20130196391-A1 PRODUCTION OF FATTY ACIDS BY HETEROLOGOUS EXPRESSION OF GENE CLUSTERS FROM MYXOBACTERIA UNIVERSITAET DES SAARLANDES (DE) 2013-08-01 US disclosed
US-4204998-A N-Amino indole derivatives having pharmacological activity SIEGFRIED AKTIENGESELLSCHAFT (CH) 1980-05-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11319303-B2 Compound used as autophagy regulator, and preparation method therefor and uses thereof ATG7, SQSTM1, BECN1 CYP4Z1 1351/4885SLC9A1 3818/4885KEAP1 1143/4885
US-20200069609-A1 METHOD FOR COVALENT BOND MODIFYING MAMMALIAN ATG8 HOMOLOGUE ATG7, ATG4A, MLST8 CYP4Z1 2599/4885SLC9A1 4799/4885KEAP1 3099/4885
US-20200190066-A1 COMPOUND USED AS AUTOPHAGY REGULATOR, AND PREPARATION METHOD THEREFOR AND USES THEREOF ATG7, SQSTM1, BECN1 CYP4Z1 1351/4885SLC9A1 3818/4885KEAP1 1143/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.