SCHEMBL16639173

SCHEMBL16639173

CN([SiH2]CC[SiH3])C1CCCCC1

nearest known ligand 0.35

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ADH1A P07327 3/20 0.35
ADH1C P00326 2/20 0.35
HRH4 Q9H3N8 1/20 0.32
HRH3 Q9Y5N1 1/20 0.32
FAAH O00519 1/20 0.32
PHGDH O43175 1/20 0.32
MGLL Q99685 1/20 0.32
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17053504 0.98 ADH1C (0.32) ADH1AADH1C
SCHEMBL17053524 0.86 ADH1A (0.41) ADH1AADH1CHRH4HRH3FAAH
SCHEMBL16639191 0.84 ADH1A (0.37) ADH1AADH1CHRH4HRH3FAAH
SCHEMBL17053526 0.84 ADH1A (0.37) ADH1AADH1CHRH4HRH3FAAH
SCHEMBL17053550 0.82 ADH1C (0.33) ADH1AADH1CHRH4HRH3FAAH
SCHEMBL17053517 0.80
SCHEMBL16582933 0.80
SCHEMBL17053573 0.79 ADH1A (0.39) ADH1AADH1CHRH4HRH3FAAH
SCHEMBL16639179 0.78 ADH1A (0.37) ADH1AADH1C
SCHEMBL27966761 0.77 ADH1A (0.39) ADH1AADH1CHRH4HRH3FAAH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3395822-A1 ORGANOAMINOSILANES AND METHODS FOR MAKING SAME Versum Materials US, LLC (US) 2018-10-31 EP disclosed
US-9758534-B2 Organoaminosilanes and methods for making same VERSUM MATERIALS US, LLC (US) 2017-09-12 US disclosed
US-9758534-B2 Organoaminosilanes and methods for making same VERSUM MATERIALS US, LLC (US) 2017-09-12 US disclosed
US-20170204120-A1 Organoaminosilanes and Methods for Making Same VERSUM MATERIALS US, LLC (US) 2017-07-20 US disclosed
EP-3095788-A2 ORGANOAMINOSILANE PRECURSORS AND METHODS FOR DEPOSITING FILMS COMPRISING SAME AIR PRODUCTS AND CHEMICALS, INC. (US) 2016-11-23 EP disclosed
US-20160168169-A1 ORGANOAMINOSILANES AND METHODS FOR MAKING SAME AIR PRODUCTS AND CHEMICALS, INC. (US) 2016-06-16 US disclosed
US-20160168169-A1 ORGANOAMINOSILANES AND METHODS FOR MAKING SAME AIR PRODUCTS AND CHEMICALS, INC. (US) 2016-06-16 US disclosed
US-20160168169-A1 ORGANOAMINOSILANES AND METHODS FOR MAKING SAME AIR PRODUCTS AND CHEMICALS, INC. (US) 2016-06-16 US disclosed
US-9233990-B2 Organoaminosilanes and methods for making same AIR PRODUCTS AND CHEMICALS, INC. (US) 2016-01-12 US disclosed
US-9233990-B2 Organoaminosilanes and methods for making same AIR PRODUCTS AND CHEMICALS, INC. (US) 2016-01-12 US disclosed
US-20150246937-A1 ORGANOAMINOSILANES AND METHODS FOR MAKING SAME AIR PRODUCTS AND CHEMICALS, INC. (US) 2015-09-03 US disclosed
US-20150246937-A1 ORGANOAMINOSILANES AND METHODS FOR MAKING SAME AIR PRODUCTS AND CHEMICALS, INC. (US) 2015-09-03 US disclosed
EP-2913334-A1 Organoaminosilanes and methods for making same AIR PRODUCTS AND CHEMICALS, INC. (US) 2015-09-02 EP disclosed
EP-2860182-A2 Organoaminosilane precursors and methods for depositing films comprising same AIR PRODUCTS AND CHEMICALS, INC. (US) 2015-04-15 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150246937-A1 ORGANOAMINOSILANES AND METHODS FOR MAKING SAME DDAH1, IDUA, DDT ADH1A 160/4885ADH1C 498/4885HRH4 753/4885
US-20170204120-A1 Organoaminosilanes and Methods for Making Same DDAH1, IDUA, DDT ADH1A 160/4885ADH1C 498/4885HRH4 753/4885
US-20160168169-A1 ORGANOAMINOSILANES AND METHODS FOR MAKING SAME DDAH1, IDUA, DDT ADH1A 160/4885ADH1C 498/4885HRH4 753/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.