Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 3/20 | 0.43 |
| ▸ | PDE4A | P27815 | 2/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.33 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16639217 | 0.93 | DHODH (0.42) | DHODHPDE4AKCNH2MAPTMALT1 | |
| SCHEMBL14361041 | 0.93 | DHODH (0.43) | DHODHPDE4AKCNH2MAPTMALT1 | |
| SCHEMBL782462 | 0.93 | DHODH (0.38) | DHODHPDE4AKCNH2MAPTMALT1 | |
| SCHEMBL782232 | 0.93 | DHODH (0.43) | DHODHPDE4AKCNH2MAPTMALT1 | |
| SCHEMBL10028777 | 0.92 | DHODH (0.40) | DHODHPDE4AKCNH2MAPTMALT1 | |
| SCHEMBL10140140 | 0.92 | SORT1 (0.39) | DHODHPDE4AKCNH2MAPTLMNA | |
| SCHEMBL14470626 | 0.91 | DHODH (0.37) | DHODHPDE4AKCNH2MAPTMALT1 | |
| SCHEMBL12438370 | 0.91 | DHODH (0.42) | DHODHPDE4AKCNH2MAPTMALT1 | |
| SCHEMBL10028768 | 0.91 | DHODH (0.43) | DHODHPDE4AKCNH2MAPTMALT1 | |
| SCHEMBL3086322 | 0.90 | DHODH (0.49) | DHODHPDE4AKCNH2MAPTMALT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 146 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10405548-B2 | Fungicidal compositions | SYNGENTA CROP PROTECTION LLC (US) | 2019-09-10 | — | — | US | disclosed |
| EP-2547665-B1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2018-07-04 | — | — | EP | disclosed |
| US-9949482-B2 | Fungicidal compositions | SYNGENTA CROP PROTECTION, LLC (US) | 2018-04-24 | — | — | US | disclosed |
| US-9771365-B2 | Spiroheterocyclic N-oxypiperidines as pesticides | SYNGENTA PARTICIPATIONS AG (CH) | 2017-09-26 | — | — | US | disclosed |
| US-9771365-B2 | Spiroheterocyclic N-oxypiperidines as pesticides | SYNGENTA PARTICIPATIONS AG (CH) | 2017-09-26 | — | — | US | disclosed |
| US-20170071205-A1 | FUNGICIDAL COMPOSITIONS | SYNGENTA CROP PROTECTION, LLC (US) | 2017-03-16 | — | — | US | disclosed |
| US-20170027173-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION, LLC (US) | 2017-02-02 | — | — | US | disclosed |
| US-20170027173-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION, LLC (US) | 2017-02-02 | — | — | US | disclosed |
| EP-2723723-B1 | N-OXY PYRAZOLO-TRIAZEPINE-DIONE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2017-02-01 | — | — | EP | disclosed |
| US-9499524-B2 | Insecticidal compounds | SYNGENTA PARTICIPATIONS AG (CH) | 2016-11-22 | — | — | US | disclosed |
| US-20070270416-A1 | Active Compound Combinations Having Insecticidal and Acaricidal Properties | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2007-11-22 | — | — | US | disclosed |
| US-20070270416-A1 | Active Compound Combinations Having Insecticidal and Acaricidal Properties | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2007-11-22 | — | — | US | disclosed |
| US-20070244073-A1 | Pesticidal Mixtures | SYNGENTA CROP PROTECTION, INC. (US) | 2007-10-18 | — | — | US | disclosed |
| US-20070244073-A1 | Pesticidal Mixtures | SYNGENTA CROP PROTECTION, INC. (US) | 2007-10-18 | — | — | US | disclosed |
| US-20070232598-A1 | Combination of Active Substances with Insecticidal Properties | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2007-10-04 | — | — | US | disclosed |
| US-20070232598-A1 | Combination of Active Substances with Insecticidal Properties | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2007-10-04 | — | — | US | disclosed |
| US-20070142327-A1 | Active compound combinations having insecticidal properties | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2007-06-21 | — | — | US | disclosed |
| US-20070142327-A1 | Active compound combinations having insecticidal properties | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2007-06-21 | — | — | US | disclosed |
| WO-2007020050-A2 | BICYCLIC BISAMIDE DERIVATIVES AND USE THEREOF AS INSECTICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2007-02-22 | — | — | WO | disclosed |
| WO-2007009661-A2 | PESTICIDAL MIXTURES CONTAINING BICYCLIC ANTHRANILAMIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2007-01-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070142327-A1 | Active compound combinations having insecticidal properties | ACHE, ANTXR2, NANP | DHODH 2787/4885PDE4A 75/4885KCNH2 1667/4885 |
| US-20170027173-A1 | INSECTICIDAL COMPOUNDS | ACHE, AADAC, CASP3 | DHODH 1693/4885PDE4A 937/4885KCNH2 1460/4885 |
| US-20070232598-A1 | Combination of Active Substances with Insecticidal Properties | ACHE, CHRM3, CHRNA2 | DHODH 3666/4885PDE4A 341/4885KCNH2 604/4885 |
| US-20070270416-A1 | Active Compound Combinations Having Insecticidal and Acaricidal Properties | AADAC, ACAA2, AAAS | DHODH 2064/4885PDE4A 467/4885KCNH2 246/4885 |
| US-20070244073-A1 | Pesticidal Mixtures | ACHE, ATL3, BPHL | DHODH 2761/4885PDE4A 501/4885KCNH2 1449/4885 |
| US-10405548-B2 | Fungicidal compositions | PIK3C3, CYP51A1, CYP1B1 | DHODH 874/4885PDE4A 504/4885KCNH2 499/4885 |
| US-20170071205-A1 | FUNGICIDAL COMPOSITIONS | PIK3C3, CYP51A1, CYP1B1 | DHODH 874/4885PDE4A 504/4885KCNH2 499/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.