SCHEMBL16639287

SCHEMBL16639287

c1ccc(-c2ccccc2N(c2ccc(-c3ccc4ccc5c(-c6ccc(N(c7ccc8ccccc8c7)c7ccccc7-c7ccccc7)cc6)ccc6ccc3c4c65)cc2)c2ccc3ccccc3c2)cc1

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 2/20 0.32
MEN1 O00255 1/20 0.32
MAPT P10636 1/20 0.32
KMT2A Q03164 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
GSTP1 P09211 1/20 0.31
HSD17B1 P14061 1/20 0.31
HSD17B2 P37059 1/20 0.31
TNF P01375 1/20 0.31
ERBB2 P04626 1/20 0.30
CYP1A2 P05177 1/20 0.30
FYN P06241 1/20 0.30
MAOA P21397 1/20 0.30
ACHE P22303 1/20 0.30
AHR P35869 1/20 0.30
PTGES O14684 2/20 0.30
ALOX5 P09917 2/20 0.30
ALDH1A1 P00352 1/20 0.30
TP53 P04637 1/20 0.30
HPGD P15428 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16639310 0.94 HSD17B1 (0.33) MEN1MAPTKMT2ASMN1; SMN2HSD17B1
SCHEMBL16639338 0.90 RXRA (0.31) MEN1MAPTKMT2ASMN1; SMN2TNF
SCHEMBL16639278 0.90 RXRA (0.31) MAPTTNFCYP1A2ALDH1A1
SCHEMBL16639634 0.90 RXRA (0.31) MEN1MAPTKMT2ASMN1; SMN2TNF
SCHEMBL16639279 0.90 RXRA (0.31) MAPTTNFCYP1A2ALDH1A1
SCHEMBL16641952 0.90 RXRA (0.31) MEN1MAPTKMT2ASMN1; SMN2TNF
SCHEMBL16639295 0.90 HSD17B1 (0.35) MAPK1MEN1MAPTKMT2ASMN1; SMN2
SCHEMBL16639340 0.89 CYP1A2 (0.35) MAPK1HSD17B1HSD17B2TNFERBB2
SCHEMBL16641958 0.89 TNF (0.32) TNF
SCHEMBL18174842 0.88 GSTP1 (0.35) MAPK1MEN1MAPTKMT2ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9293712-B2 Disubstituted pyrene compounds with amino group containing ortho aryl group and devices containing the same UNIVERSAL DISPLAY CORPORATION (US) 2016-03-22 US disclosed
US-9293712-B2 Disubstituted pyrene compounds with amino group containing ortho aryl group and devices containing the same UNIVERSAL DISPLAY CORPORATION (US) 2016-03-22 US disclosed
US-20150102321-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION 2015-04-16 US disclosed
US-20150102321-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION 2015-04-16 US disclosed
US-20150102290-A1 DISUBSTITUTED PYRENE COMPOUNDS WITH AMINO GROUP CONTAINING ORTHO ARYL GROUP UNIVERSAL DISPLAY CORPORATION (US) 2015-04-16 US disclosed
US-20150102290-A1 DISUBSTITUTED PYRENE COMPOUNDS WITH AMINO GROUP CONTAINING ORTHO ARYL GROUP UNIVERSAL DISPLAY CORPORATION (US) 2015-04-16 US disclosed