SCHEMBL16639288

SCHEMBL16639288

c1ccc(-c2ccccc2N(c2ccc(-c3ccc4ccc5c(-c6ccc(N(c7ccc8oc9ccccc9c8c7)c7ccccc7-c7ccccc7)cc6)ccc6ccc3c4c65)cc2)c2ccc3oc4ccccc4c3c2)cc1

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.33
ALDH1A1 P00352 4/20 0.33
MAPT P10636 3/20 0.33
HPGD P15428 3/20 0.33
KMT2A Q03164 3/20 0.33
RAB9A P51151 2/20 0.33
MEN1 O00255 2/20 0.33
NPC1 O15118 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
HSP90AA1 P07900 1/20 0.32
HSP90AB1 P08238 1/20 0.32
ALOX15 P16050 1/20 0.32
TSHR P16473 1/20 0.32
CASP1 P29466 1/20 0.32
CASP7 P55210 1/20 0.32
HSD17B10 Q99714 1/20 0.32
MAOB P27338 1/20 0.32
AHR P35869 3/20 0.31
CYP1A1 P04798 1/20 0.31
CYP1A2 P05177 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16639324 0.96 KDM4E (0.31) KDM4EALDH1A1MAPTHPGDKMT2A
SCHEMBL16639339 0.95 PGR (0.30) KDM4EALDH1A1MAPTHPGDKMT2A
SCHEMBL16639297 0.95 PGR (0.33) KDM4EALDH1A1MAPTHPGDKMT2A
SCHEMBL16639291 0.91 PGR (0.34) KDM4EALDH1A1MAPTHPGDKMT2A
SCHEMBL16639303 0.91 MAOB (0.33) KDM4EALDH1A1MAPTHPGDHSD17B10
SCHEMBL22433793 0.90 PLA2G2A (0.33) KDM4EALDH1A1MAPTHPGDHSP90AA1
SCHEMBL23511840 0.89 KDM4E (0.35) KDM4EALDH1A1MAPTHPGDKMT2A
SCHEMBL16639638 0.89 PGR (0.33) KDM4EALDH1A1MAPTHPGDKMT2A
SCHEMBL25608187 0.88 NPC1 (0.40) KDM4EALDH1A1MAPTHPGDKMT2A
SCHEMBL23511845 0.88 PGR (0.34) KDM4EALDH1A1MAPTHPGDKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9293712-B2 Disubstituted pyrene compounds with amino group containing ortho aryl group and devices containing the same UNIVERSAL DISPLAY CORPORATION (US) 2016-03-22 US disclosed
US-9293712-B2 Disubstituted pyrene compounds with amino group containing ortho aryl group and devices containing the same UNIVERSAL DISPLAY CORPORATION (US) 2016-03-22 US disclosed
US-20150102321-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION 2015-04-16 US disclosed
US-20150102290-A1 DISUBSTITUTED PYRENE COMPOUNDS WITH AMINO GROUP CONTAINING ORTHO ARYL GROUP UNIVERSAL DISPLAY CORPORATION (US) 2015-04-16 US disclosed
US-20150102290-A1 DISUBSTITUTED PYRENE COMPOUNDS WITH AMINO GROUP CONTAINING ORTHO ARYL GROUP UNIVERSAL DISPLAY CORPORATION (US) 2015-04-16 US disclosed
US-20150102321-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION 2015-04-16 US disclosed