SCHEMBL16639368

SCHEMBL16639368

Cc1ccc(C(C)(c2ccc(OS(=O)(=O)C(F)(F)F)cc2)c2ccc(-c3ccc4c(c3)CC4)cc2)cc1

nearest known ligand 0.40

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
DRD2 P14416 9/20 0.39
DRD3 P35462 9/20 0.39
HTR1D P28221 1/20 0.39
KIF11 P52732 1/20 0.39
CA2 P00918 3/20 0.36
CA12 O43570 2/20 0.36
CA1 P00915 1/20 0.35
CA9 Q16790 1/20 0.35
DPP4 P27487 1/20 0.34
ALDH1A1 P00352 1/20 0.34
LMNA P02545 1/20 0.34
THRB P10828 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
STS P08842 1/20 0.34
KCNA1 Q09470 1/20 0.34
KCNAB1 Q14722 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16640025 0.95 KIF11 (0.42) DRD2DRD3HTR1DKIF11CA2
SCHEMBL16658435 0.89 DRD2 (0.40) DRD2DRD3HTR1DKIF11
SCHEMBL29308768 0.82 STS (0.47) DRD2DRD3HTR1DKIF11CA2
SCHEMBL16450321 0.80 CA1 (0.43) DRD2DRD3KIF11CA2CA1
SCHEMBL18328350 0.79 DRD2 (0.37) DRD2DRD3HTR1DKIF11SMN1; SMN2
SCHEMBL15165487 0.75 CA1 (0.47) DRD2DRD3KIF11CA2CA1
SCHEMBL2750188 0.75 CA2 (0.57) DRD2DRD3HTR1DKIF11CA2
SCHEMBL18553114 0.74 CA2 (0.40) DRD2DRD3KIF11CA2CA12
Biphenyl SCHEMBL114434 0.74 CA2 (0.50) KIF11CA2CA12CA1CA9
SCHEMBL16373430 0.74 PTPN11 (0.46) DRD2DRD3HTR1DKIF11CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9391278-B2 Polymer compound, charge-transporting polymer, composition for organic electroluminescent element, organic electroluminescent element, organic EL display device, and organic EL light MITSUBISHI CHEMICAL CORPORATION (JP) 2016-07-12 US disclosed
US-20150102334-A1 POLYMER COMPOUND, CHARGE-TRANSPORTING POLYMER, COMPOSITION FOR ORGANIC ELECTROLUMINESCENT ELEMENT, ORGANIC ELECTROLUMINESCENT ELEMENT, ORGANIC EL DISPLAY DEVICE, AND ORGANIC EL LIGHT MITSUBISHI CHEMICAL CORPORATION (JP) 2015-04-16 US disclosed