Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 1/20 | 0.53 |
| ▸ | KDM1A | O60341 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.47 |
| ▸ | NPC1 | O15118 | 7/20 | 0.47 |
| ▸ | RAB9A | P51151 | 6/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.47 |
| ▸ | MAPT | P10636 | 6/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | CASP3 | P42574 | 1/20 | 0.46 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.46 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.46 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15590654 | 0.83 | KDM1A (0.54) | PTGESKDM1AALDH1A1KDM4ENPC1 | |
| SCHEMBL21889082 | 0.81 | KDM1A (0.51) | PTGESKDM1AALDH1A1KDM4ENPC1 | |
| SCHEMBL15590651 | 0.80 | NPY5R (0.48) | PTGESKDM1AALDH1A1KDM4ENPC1 | |
| SCHEMBL5999686 | 0.80 | KDM4E (0.59) | KDM1AALDH1A1KDM4ESMN1; SMN2MAPT | |
| SCHEMBL13620586 | 0.79 | NPY5R (0.50) | PTGESKDM1AALDH1A1KDM4ENPC1 | |
| SCHEMBL16639586 | 0.77 | NPC1 (0.50) | PTGESALDH1A1KDM4ENPC1RAB9A | |
| SCHEMBL22870164 | 0.77 | KDM4E (0.56) | KDM1AALDH1A1KDM4ESMN1; SMN2MAPT | |
| SCHEMBL14114045 | 0.76 | NPY5R (0.57) | PTGESKDM1AALDH1A1KDM4EMAPT | |
| SCHEMBL21889085 | 0.76 | METAP2 (0.49) | PTGESKDM1ARAB9AMEN1KMT2A | |
| SCHEMBL13620582 | 0.76 | KDM4E (0.53) | PTGESKDM1AALDH1A1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2856528-B1 | METAL COMPLEXES COMPRISING CONDENSED HETEROAROMATIC RINGS | MERCK PATENT GMBH (DE) | 2019-07-03 | — | — | EP | disclosed |
| US-9879177-B2 | Metal complexes comprising condensed heteroaromatic rings | MERCK PATENT GMBH (DE) | 2018-01-30 | — | — | US | disclosed |
| US-9879177-B2 | Metal complexes comprising condensed heteroaromatic rings | MERCK PATENT GMBH (DE) | 2018-01-30 | — | — | US | disclosed |
| US-20150105843-A1 | METAL COMPLEXES COMPRISING CONDENSED HETEROAROMATIC RINGS | UDC IRELAND LIMITED (IE) | 2015-04-16 | — | — | US | disclosed |
| US-20150105843-A1 | METAL COMPLEXES COMPRISING CONDENSED HETEROAROMATIC RINGS | UDC IRELAND LIMITED (IE) | 2015-04-16 | — | — | US | disclosed |