SCHEMBL21889085

SCHEMBL21889085

CCn1c2cc(-c3cccc(-c4ccccc4)n3)ccc2c2ccc(-c3cccc(-c4ccccc4)n3)cc21

nearest known ligand 0.49

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
METAP2 P50579 9/20 0.49
MEN1 O00255 1/20 0.48
RAB9A P51151 1/20 0.48
KMT2A Q03164 1/20 0.48
KDM1A O60341 1/20 0.45
NLRP3 Q96P20 1/20 0.44
NPY5R Q15761 3/20 0.44
ADORA2A P29274 1/20 0.42
PTGES O14684 1/20 0.41
ADORA1 P30542 1/20 0.40
MAPK14 Q16539 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21889082 0.96 KDM1A (0.51) METAP2MEN1RAB9AKMT2AKDM1A
SCHEMBL21888858 0.92 NPY5R (0.50) METAP2MEN1RAB9AKMT2AKDM1A
SCHEMBL21076076 0.82 METAP2 (0.48) METAP2MEN1KMT2AKDM1ANLRP3
SCHEMBL13620583 0.78 KDM4E (0.54) METAP2MEN1KMT2AKDM1ANPY5R
SCHEMBL13620587 0.78 KDM4E (0.54) METAP2MEN1KMT2AKDM1ANPY5R
SCHEMBL16865779 0.77 KDM1A (0.50) METAP2MEN1KMT2AKDM1ANPY5R
SCHEMBL24667916 0.76 TSPO (0.53) METAP2MEN1KMT2AKDM1ANLRP3
SCHEMBL14114045 0.76 NPY5R (0.57) MEN1KMT2AKDM1ANPY5RPTGES
SCHEMBL16639587 0.76 PTGES (0.53) MEN1RAB9AKMT2AKDM1ANPY5R
SCHEMBL14805227 0.75 NPY5R (0.59) MEN1KMT2ANPY5RPTGES

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11584739-B2 Composition of matter for use in organic light-emitting diodes KYULUX, INC. (JP) 2023-02-21 US disclosed
US-20200115364-A1 COMPOSITION OF MATTER FOR USE IN ORGANIC LIGHT-EMITTING DIODES KYULUX, INC. (JP) 2020-04-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200115364-A1 COMPOSITION OF MATTER FOR USE IN ORGANIC LIGHT-EMITTING DIODES CRY2, CLTB, CYBA METAP2 1252/4885MEN1 3395/4885RAB9A 3388/4885
US-11584739-B2 Composition of matter for use in organic light-emitting diodes CRY2, CLTB, CYBA METAP2 1252/4885MEN1 3395/4885RAB9A 3388/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.