Sugi Predict

Sugi Predict / Compounds / SCHEMBL1663961

SCHEMBL1663961

SCHEMBL1663961

Clc1cnnc2ccccc12

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ GPR3 P46089 2/20 0.50
▸ MAOA P21397 1/20 0.43
▸ MAOB P27338 1/20 0.43
▸ CYP1A2 P05177 4/20 0.40
▸ CYP2A6 P11509 3/20 0.40
▸ TGFBR1 P36897 1/20 0.40
▸ ALDH1A1 P00352 3/20 0.39
▸ KDM4E B2RXH2 3/20 0.39
▸ TDP1 Q9NUW8 3/20 0.39
▸ MEN1 O00255 1/20 0.39
▸ GLA P06280 1/20 0.39
▸ GAA P10253 1/20 0.39
▸ MAPT P10636 1/20 0.39
▸ MAPK1 P28482 1/20 0.39
▸ KMT2A Q03164 1/20 0.39
▸ NOS1 P29475 1/20 0.39
▸ PDE4A P27815 1/20 0.39
▸ PDE4B Q07343 1/20 0.39
▸ PDE4C Q08493 1/20 0.39
▸ PDE4D Q08499 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30701961 1.00 GPR3 (0.50) GPR3MAOAMAOBCYP1A2CYP2A6
SCHEMBL9118110 0.87 KMT2A (0.42) GPR3MAOAMAOBCYP1A2TGFBR1
SCHEMBL15028830 0.74 NR4A2 (0.40) CYP1A2ALDH1A1TDP1MEN1MAPT
SCHEMBL6096600 0.74 SMN1; SMN2 (0.43) ALDH1A1TDP1MAPTPIK3CDLMNA
SCHEMBL30950666 0.74 SMN1; SMN2 (0.43) ALDH1A1TDP1MAPTPIK3CDLMNA
SCHEMBL3883304 0.73 GPR3 (0.50) GPR3MAOAMAOBCYP1A2TGFBR1
SCHEMBL2013184 0.73 GPR3 (0.50) GPR3MAOAMAOBCYP1A2TGFBR1
SCHEMBL276531 0.73 GPR3 (0.50) GPR3MAOAMAOBCYP1A2TGFBR1
SCHEMBL21532813 0.73 GPR3 (0.50) GPR3MAOAMAOBCYP1A2TGFBR1
SCHEMBL276532 0.73 GPR3 (0.50) GPR3MAOACYP1A2TGFBR1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 156 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-4187677-A — — None — — JP disclosed
US-12410183-B2 Sars-cov2 main protease inhibitors GILEAD SCIENCES, INC. (US) 2025-09-09 — — US disclosed
US-12391673-B2 LANCL ligands NIMMUNE BIOPHARMA, INC. (US) 2025-08-19 — — US disclosed
EP-4565574-A1 SARS-COV2 MAIN PROTEASE INHIBITORS GILEAD SCIENCES, INC. (US) 2025-06-11 — — EP disclosed
CN-119731159-A SARS-CoV2 main proteinase inhibitor 吉利德科学公司 2025-03-28 — — CN disclosed
US-20250042915-A1 SARS-COV2 MAIN PROTEASE INHIBITORS GILEAD SCIENCES, INC. 2025-02-06 — — US disclosed
EP-3558969-B1 PYRAZOLE DERIVATIVES AS MALT1 INHIBITORS JANSSEN PHARMACEUTICA NV (BE) 2024-09-18 — — EP disclosed
US-12091420-B2 SARS-COV2 main protease inhibitors GILEAD SCIENCES, INC. (US) 2024-09-17 — — US disclosed
US-12077521-B2 Pyrazole derivatives as MALT1 inhibitors JANSSEN PHARMACEUTICA NV (BE) 2024-09-03 — — US disclosed
US-20240239807-A1 SARS-COV2 MAIN PROTEASE INHIBITORS GILEAD SCIENCES, INC. 2024-07-18 — — US disclosed
US-4994474-A Hypotensive agents SANOFI (FR) 1991-02-19 — — US disclosed
US-4957925-A HYPOTENSIVE AGENTS, ANTIARRHYTHMIA AGENTS, TREATMENT OF ANGINA SANOFI (FR) 1990-09-18 — — US disclosed
CN-1006386-B PROCESS FOR PRODUCTION OF VINYL CHLORIDE POLYMER SHINETSU CHEM IND CO (JP) 1990-01-10 — — CN disclosed
EP-0172427-B1 PROCESS FOR PRODUCTION OF VINYL CHLORIDE POLYMER Shin-Etsu Chemical Co., Ltd. (JP) 1989-07-05 — — EP disclosed
EP-0302793-A2 Aralkylaminoalkoxyphenyl derivatives, process of preparation and compositions containing the same ELF SANOFI (FR) 1989-02-08 — — EP disclosed
US-4758639-A Process for production of vinyl polymer SHIN-ETSU CHEMICAL CO., LTD. (JP) 1988-07-19 — — US disclosed
US-4757124-A Suspension or emulsion polymerizing vinyl chloride monomer or mixture of vinyl chloride with vinyl monomer copolymerizable therewith in reactor with walls coated with antiscaling compound containing dye or pigments SHIN-ETSU CHEMICAL CO., LTD. (JP) 1988-07-12 — — US disclosed
CN-85107531-A Process for producing vinyl chloride polymer — 1987-01-21 — — CN disclosed
EP-0172427-A2 Process for production of vinyl chloride polymer Shin-Etsu Chemical Co., Ltd. (JP) 1986-02-26 — — EP disclosed
US-4503227-A HEAT SENSITIVE OR PRESSURE SENSITIVE RECORDING CIBA-GEIGY CORPORATION (US) 1985-03-05 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250042915-A1 SARS-COV2 MAIN PROTEASE INHIBITORS ACE2, TMPRSS2, ACE GPR3 3606/4885MAOA 2527/4885MAOB 1582/4885
US-12091420-B2 SARS-COV2 main protease inhibitors ACE2, TMPRSS2, ACE GPR3 3606/4885MAOA 2527/4885MAOB 1582/4885
US-12410183-B2 Sars-cov2 main protease inhibitors ACE2, TMPRSS2, ACE GPR3 3606/4885MAOA 2527/4885MAOB 1582/4885
US-12391673-B2 LANCL ligands LANCL2, LANCL1, ACSL1 GPR3 998/4885MAOA 4867/4885MAOB 4833/4885
US-20240239807-A1 SARS-COV2 MAIN PROTEASE INHIBITORS ACE2, TMPRSS2, ACE GPR3 3606/4885MAOA 2527/4885MAOB 1582/4885
US-12077521-B2 Pyrazole derivatives as MALT1 inhibitors MALT1, PPP3R1, SQSTM1 GPR3 3153/4885MAOA 4218/4885MAOB 3636/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.