Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABHD16A | O95870 | 1/20 | 0.46 |
| ▸ | CES2 | O00748 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | FASN | P49327 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.39 |
| ▸ | HPSE | Q9Y251 | 2/20 | 0.39 |
| ▸ | ACP1 | P24666 | 2/20 | 0.39 |
| ▸ | CDC25B | P30305 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.39 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18784040 | 1.00 | ABHD16A (0.46) | ABHD16ACES2POLBFASNPTPN1 | |
| SCHEMBL15598670 | 0.98 | ABHD16A (0.48) | ABHD16ACES2POLBFASNPTPN1 | |
| SCHEMBL16639647 | 0.98 | ABHD16A (0.48) | ABHD16ACES2POLBFASNPTPN1 | |
| SCHEMBL18784042 | 0.98 | ABHD16A (0.48) | ABHD16ACES2POLBFASNPTPN1 | |
| SCHEMBL5674415 | 0.98 | ABHD16A (0.48) | ABHD16ACES2POLBFASNPTPN1 | |
| SCHEMBL15598671 | 0.98 | ABHD16A (0.48) | ABHD16ACES2POLBFASNPTPN1 | |
| SCHEMBL3104384 | 0.79 | CES2 (0.45) | ABHD16ACES2POLBFASNPTPN1 | |
| SCHEMBL18784041 | 0.78 | ABHD16A (0.42) | ABHD16ACES2POLBFASNPTPN1 | |
| SCHEMBL7559916 | 0.78 | CES2 (0.52) | ABHD16ACES2POLBFASNPTPN1 | |
| SCHEMBL18784044 | 0.77 | ABHD16A (0.44) | ABHD16ACES2POLBFASNPTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9265706-B2 | Lichesterinic acid and the derivatives of same as pigmentation inhibitors | Centre National de la Recherche Scientifique—CNRS (FR) | 2016-02-23 | — | — | US | disclosed |
| US-9265706-B2 | Lichesterinic acid and the derivatives of same as pigmentation inhibitors | Centre National de la Recherche Scientifique—CNRS (FR) | 2016-02-23 | — | — | US | disclosed |
| US-20150105459-A1 | LICHESTERINIC ACID AND THE DERIVATIVES OF SAME AS PIGMENTATION INHIBITORS | UNIVERSITE DE RENNES (FR) | 2015-04-16 | — | — | US | disclosed |
| US-20150105459-A1 | LICHESTERINIC ACID AND THE DERIVATIVES OF SAME AS PIGMENTATION INHIBITORS | UNIVERSITE DE RENNES (FR) | 2015-04-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150105459-A1 | LICHESTERINIC ACID AND THE DERIVATIVES OF SAME AS PIGMENTATION INHIBITORS | TYR, MITF, ALDH7A1 | ABHD16A 1568/4885CES2 4493/4885POLB 3467/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.