SCHEMBL16640270

SCHEMBL16640270

c1ccc(P(C2CCCCC2)C2CCCCC2)c(C(c2ccccc2P(C2CCCCC2)C2CCCCC2)c2ccccc2P(C2CCCCC2)C2CCCCC2)c1

nearest known ligand 0.36

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ROCK2 O75116 1/20 0.36
ACP3 P15309 1/20 0.31
IDO1 P14902 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2848628 0.85 ROCK2 (0.38) ROCK2ACP3IDO1
SCHEMBL1315359 0.83 ROCK2 (0.35) ROCK2IDO1
SCHEMBL16694758 0.83 ROCK2 (0.44) ROCK2
SCHEMBL8000143 0.81 ROCK2 (0.35) ROCK2
SCHEMBL2846316 0.81 TAAR1 (0.34) ROCK2ACP3IDO1
SCHEMBL1314189 0.81 ROCK2 (0.33) ROCK2
SCHEMBL19170233 0.80 ROCK2 (0.37) ROCK2
SCHEMBL17583591 0.79 ROCK2 (0.33) ROCK2
SCHEMBL16694354 0.79 SLC6A2 (0.34) ROCK2
SCHEMBL520084 0.78 BCHE (0.37) ROCK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9815694-B2 Catalytic ammonia synthesis by transition metal molecular complexes CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2017-11-14 US disclosed
US-20150104371-A1 CATALYTIC AMMONIA SYNTHESIS BY TRANSITION METAL MOLECULAR COMPLEXES CALIFORNIA INSTITUTE OF TECHNOLOGY 2015-04-16 US disclosed