Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 2/20 | 0.32 |
| ▸ | METAP2 | P50579 | 3/20 | 0.31 |
| ▸ | METAP1 | P53582 | 2/20 | 0.31 |
| ▸ | DPP4 | P27487 | 1/20 | 0.30 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.30 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.30 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.30 |
| ▸ | ACP3 | P15309 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16640270 | 0.85 | ROCK2 (0.36) | ROCK2IDO1ACP3 | |
| SCHEMBL2846316 | 0.81 | TAAR1 (0.34) | ROCK2IDO1METAP2METAP1ACP3 | |
| SCHEMBL1315359 | 0.80 | ROCK2 (0.35) | ROCK2IDO1 | |
| SCHEMBL16694758 | 0.80 | ROCK2 (0.44) | ROCK2 | |
| SCHEMBL8000143 | 0.78 | ROCK2 (0.35) | ROCK2 | |
| SCHEMBL1314189 | 0.78 | ROCK2 (0.33) | ROCK2 | |
| SCHEMBL19170233 | 0.77 | ROCK2 (0.37) | ROCK2 | |
| SCHEMBL17583591 | 0.77 | ROCK2 (0.33) | ROCK2 | |
| SCHEMBL16694354 | 0.76 | SLC6A2 (0.34) | ROCK2 | |
| SCHEMBL14905782 | 0.76 | GAA (0.43) | ROCK2IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8436111-B2 | Nickel catalyst system for the preparation of high CIS polybutadiene | BRIDGESTONE CORPORATION (JP) | 2013-05-07 | — | — | US | claimed |
| US-20100093920-A1 | NICKEL CATALYST SYSTEM FOR THE PREPARATION OF HIGH CIS POLYBUTADIENE | BRIDGESTONE CORPORATION (JP) | 2010-04-15 | — | — | US | claimed |
| US-8436111-B2 | Nickel catalyst system for the preparation of high CIS polybutadiene | BRIDGESTONE CORPORATION (JP) | 2013-05-07 | — | — | US | disclosed |
| US-20100093920-A1 | NICKEL CATALYST SYSTEM FOR THE PREPARATION OF HIGH CIS POLYBUTADIENE | BRIDGESTONE CORPORATION (JP) | 2010-04-15 | — | — | US | disclosed |