Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16694354 | 0.98 | SLC6A2 (0.34) | ROCK2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL16694399 | 0.81 | ALDH1A1 (0.34) | ROCK2MEN1MAPTRAB9AKMT2A | |
| SCHEMBL16640270 | 0.81 | ROCK2 (0.36) | ROCK2 | |
| SCHEMBL16694758 | 0.80 | ROCK2 (0.44) | ROCK2SLC6A2SLC6A4SLC6A3RAB9A | |
| SCHEMBL2848628 | 0.78 | ROCK2 (0.38) | ROCK2 | |
| SCHEMBL1315359 | 0.76 | ROCK2 (0.35) | ROCK2MEN1MAPTKMT2ALMNA | |
| SCHEMBL19170233 | 0.76 | ROCK2 (0.37) | ROCK2SLC6A2SLC6A4MEN1MAPT | |
| SCHEMBL6651864 | 0.75 | SMN1; SMN2 (0.42) | RAB9AKMT2ALMNANPC1ALDH1A1 | |
| SCHEMBL29527648 | 0.75 | SMN1; SMN2 (0.42) | RAB9AKMT2ALMNANPC1ALDH1A1 | |
| SCHEMBL2846316 | 0.74 | TAAR1 (0.34) | ROCK2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6124476-A | SUZUKI CROSS-COUPLING REACTIONS. PHOSPHINOBENZALDEHYDES AND ACETALS | SYMYX TECHNOLOGIES, INC. (US) | 2000-09-26 | — | — | US | disclosed |
| WO-2000008032-A1 | CATALYST LIGANDS USEFUL FOR CROSS-COUPLING REACTIONS | SYMYX TECHNOLOGIES, INC. (US) | 2000-02-17 | — | — | WO | disclosed |