SCHEMBL16640318

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL13236508	0.86	RXFP1 (0.47)	PDE4APDE4BPDE4CPDE4DKDM4E
	SCHEMBL23490972	0.85	PPARG (0.43)	PDE4APDE4BPDE4CPDE4DKDM4E
	SCHEMBL11978691	0.83	CYP2C19 (0.49)	PDE4APDE4BPDE4CPDE4DKDM4E
	SCHEMBL5021418	0.83	AKT1 (0.46)	PDE4APDE4BPDE4CPDE4DKDM4E
	SCHEMBL261813	0.83	KDM4E (0.47)	PDE4APDE4BPDE4CPDE4DKDM4E
	SCHEMBL5021401	0.82	KDM4E (0.61)	PDE4APDE4BPDE4CPDE4DKDM4E
	SCHEMBL16640348	0.82	L3MBTL1 (0.41)	PDE4APDE4BPDE4CPDE4DKDM4E
	SCHEMBL1102414	0.82	KDM4E (0.59)	KDM4EATML3MBTL1MAPTALDH1A1
	SCHEMBL16640316	0.82	GRM4 (0.35)	PDE4APDE4BPDE4CPDE4DKDM4E
	SCHEMBL16640330	0.82	PDE4A (0.37)	PDE4APDE4BPDE4CPDE4DKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.