Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 6/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 6/20 | 0.37 |
| ▸ | PDE4C | Q08493 | 5/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 5/20 | 0.37 |
| ▸ | FEN1 | P39748 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16640324 | 0.87 | ATM (0.46) | KDM4EATML3MBTL1CYP2C19ALDH1A1 | |
| SCHEMBL16640329 | 0.84 | HTT (0.35) | PDE4APDE4BPDE4CPDE4DKDM4E | |
| SCHEMBL16644617 | 0.83 | PDE4B (0.44) | PDE4APDE4BPDE4CPDE4DFEN1 | |
| SCHEMBL16640318 | 0.82 | PDE4A (0.41) | PDE4APDE4BPDE4CPDE4DFEN1 | |
| SCHEMBL16640323 | 0.81 | MAOA (0.43) | KDM4EATML3MBTL1HDAC3HDAC2 | |
| SCHEMBL16640321 | 0.81 | CDK4 (0.38) | KDM4EATML3MBTL1KCNH2CYP1A2 | |
| SCHEMBL15394768 | 0.80 | KDM4E (0.38) | PDE4APDE4BPDE4CPDE4DFEN1 | |
| SCHEMBL21453894 | 0.79 | USP14 (0.36) | KDM4EL3MBTL1MAPTHTT | |
| SCHEMBL11978691 | 0.77 | CYP2C19 (0.49) | PDE4APDE4BPDE4CPDE4DFEN1 | |
| SCHEMBL27446451 | 0.76 | PDE10A (0.40) | FEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11189808-B2 | Platinum complexes and devices | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2021-11-30 | — | — | US | disclosed |
| US-20200152891-A1 | PLATINUM COMPLEXES AND DEVICES | UNIV ARIZONA STATE (US) | 2020-05-14 | — | — | US | disclosed |
| US-10566553-B2 | Platinum complexes and devices | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2020-02-18 | — | — | US | disclosed |
| US-9947881-B2 | Platinum complexes and devices | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2018-04-17 | — | — | US | disclosed |
| US-9947881-B2 | Platinum complexes and devices | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2018-04-17 | — | — | US | disclosed |
| US-20170012224-A1 | PLATINUM COMPLEXES AND DEVICES | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY | 2017-01-12 | — | — | US | disclosed |
| US-9385329-B2 | Platinum complexes and devices | Arizona Board of Regents on behalf of Arizona State University and Universal Display Corporation (US) | 2016-07-05 | — | — | US | disclosed |
| US-20150105556-A1 | PLATINUM COMPLEXES AND DEVICES | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY | 2015-04-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11189808-B2 | Platinum complexes and devices | OXA1L, OCIAD1, OCIAD2 | PDE4A 4870/4885PDE4B 4878/4885PDE4C 4843/4885 |
| US-10566553-B2 | Platinum complexes and devices | OXA1L, OCIAD1, OCIAD2 | PDE4A 4870/4885PDE4B 4878/4885PDE4C 4843/4885 |
| US-20200152891-A1 | PLATINUM COMPLEXES AND DEVICES | OXA1L, OCIAD1, OCIAD2 | PDE4A 4870/4885PDE4B 4878/4885PDE4C 4843/4885 |
| US-20170012224-A1 | PLATINUM COMPLEXES AND DEVICES | OXA1L, OCIAD1, OCIAD2 | PDE4A 4870/4885PDE4B 4878/4885PDE4C 4843/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.