SCHEMBL16640348

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL12383087	0.86	RXFP1 (0.47)	L3MBTL1KDM4EATMRENKMT2A
	SCHEMBL20172101	0.85	KDM4E (0.41)	L3MBTL1KDM4EATMRENKMT2A
	SCHEMBL11978685	0.83	ALDH1A1 (0.47)	L3MBTL1KDM4EATMKMT2ATDP1
	SCHEMBL13141973	0.83	KDM4E (0.47)	L3MBTL1KDM4EATMPDE4APDE4B
	SCHEMBL261831	0.83	KDM4E (0.47)	L3MBTL1KDM4EATMPDE4APDE4B
	SCHEMBL12396559	0.82	L3MBTL1 (0.61)	L3MBTL1KDM4EATMRENPDE4A
	SCHEMBL16640318	0.82	PDE4A (0.41)	L3MBTL1KDM4EATMKMT2APDE4A
	SCHEMBL1102414	0.82	KDM4E (0.59)	L3MBTL1KDM4EATMTRPV4KMT2A
	SCHEMBL16640329	0.82	HTT (0.35)	L3MBTL1KDM4EATMRENKMT2A
	SCHEMBL16640319	0.82	GRM4 (0.35)	L3MBTL1KDM4EATMRENTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.