SCHEMBL16640335

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL16640317	0.91	KDM4E (0.44)	MAOAMAOBACHEKDM4EATM
	SCHEMBL12383089	0.86	RXFP1 (0.47)	MAOAMAOBACHEKDM4EATM
	SCHEMBL1102414	0.86	KDM4E (0.59)	KDM4EATML3MBTL1PTPN1NOTUM
	SCHEMBL11978692	0.83	MAOA (0.50)	MAOAMAOBACHEKDM4EATM
	SCHEMBL4570443	0.83	MAOA (0.53)	MAOAMAOBACHEKDM4EATM
	SCHEMBL15907062	0.83	MAOA (0.53)	MAOAMAOBACHEKDM4EATM
	SCHEMBL12098614	0.82	KDM4E (0.67)	MAOAMAOBACHEKDM4EATM
	SCHEMBL16640323	0.82	MAOA (0.43)	MAOAMAOBACHEKDM4EATM
	SCHEMBL16640315	0.82	MAOA (0.43)	MAOAMAOBACHECYP2D6DDB1
	SCHEMBL9916266	0.81	KDM4E (0.53)	KDM4EATML3MBTL1PTPN1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.