SCHEMBL16640317

SCHEMBL16640317

CC(C)c1ccc(-n2c3ccccc3c3ccncc32)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.44
ATM Q13315 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
KCNH2 Q12809 1/20 0.41
PTPN1 P18031 2/20 0.39
KDR P35968 1/20 0.38
CDK4 P11802 1/20 0.37
CDK6 Q00534 1/20 0.37
MAOA P21397 4/20 0.37
MAOB P27338 4/20 0.37
IDO1 P14902 1/20 0.37
ACHE P22303 1/20 0.37
NOTUM Q6P988 1/20 0.36
ROCK2 O75116 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
ALDH1A1 P00352 1/20 0.36
LMNA P02545 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
NFATC1 O95644 1/20 0.35
GSK3B P49841 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16640335 0.91 MAOA (0.47) KDM4EATML3MBTL1PTPN1KDR
SCHEMBL12383073 0.86 RXFP1 (0.47) KDM4EATML3MBTL1KCNH2PTPN1
SCHEMBL1102414 0.86 KDM4E (0.59) KDM4EATML3MBTL1PTPN1NOTUM
SCHEMBL11978684 0.83 KDM4E (0.48) KDM4EATML3MBTL1KCNH2CDK4
SCHEMBL15263336 0.83 KDM4E (0.48) KDM4EATML3MBTL1KCNH2CDK4
SCHEMBL261830 0.83 KDM4E (0.52) KDM4EATML3MBTL1KCNH2CDK4
SCHEMBL15428469 0.82 KDM4E (0.67) KDM4EATML3MBTL1KCNH2CDK4
SCHEMBL22460749 0.82 MAPK13 (0.38) KDM4EATML3MBTL1KCNH2PTPN1
SCHEMBL16640321 0.82 CDK4 (0.38) KDM4EATML3MBTL1KCNH2CDK4
SCHEMBL16640320 0.82 MKNK1 (0.35) KDRMAOAMAOBIDO1ACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11189808-B2 Platinum complexes and devices ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) 2021-11-30 US disclosed
US-20200152891-A1 PLATINUM COMPLEXES AND DEVICES UNIV ARIZONA STATE (US) 2020-05-14 US disclosed
US-9947881-B2 Platinum complexes and devices ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) 2018-04-17 US disclosed
US-9385329-B2 Platinum complexes and devices Arizona Board of Regents on behalf of Arizona State University and Universal Display Corporation (US) 2016-07-05 US disclosed
US-20150105556-A1 PLATINUM COMPLEXES AND DEVICES ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY 2015-04-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11189808-B2 Platinum complexes and devices OXA1L, OCIAD1, OCIAD2 KDM4E 4835/4885ATM 1739/4885L3MBTL1 1502/4885
US-20200152891-A1 PLATINUM COMPLEXES AND DEVICES OXA1L, OCIAD1, OCIAD2 KDM4E 4835/4885ATM 1739/4885L3MBTL1 1502/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.