SCHEMBL16640345

SCHEMBL16640345

CC(C)n1c2ccncc2c2cnccc21

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
USP2 O75604 1/20 0.46
HTT P42858 1/20 0.46
NCOA1 Q15788 1/20 0.46
NCOA3 Q9Y6Q9 1/20 0.46
DYRK1A Q13627 3/20 0.42
NFATC1 O95644 2/20 0.42
GSK3B P49841 2/20 0.42
MAOA P21397 5/20 0.41
MAOB P27338 5/20 0.41
ACHE P22303 2/20 0.41
CYP2D6 P10635 1/20 0.38
UTS2R Q9UKP6 1/20 0.37
TDP1 Q9NUW8 2/20 0.37
MAPT P10636 1/20 0.37
TSHR P16473 1/20 0.37
MAPK1 P28482 1/20 0.37
CASP1 P29466 1/20 0.37
CASP7 P55210 1/20 0.37
ATM Q13315 1/20 0.37
POLB P06746 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16640336 0.92 DYRK1A (0.45) USP2HTTNCOA1NCOA3DYRK1A
SCHEMBL16640343 0.91 MAOA (0.54) USP2HTTNCOA1NCOA3MAOA
SCHEMBL16640338 0.83 DYRK1A (0.50) USP2HTTNCOA1NCOA3DYRK1A
SCHEMBL16640331 0.81 USP2 (0.43) USP2HTTNCOA1NCOA3DYRK1A
SCHEMBL16640349 0.81 USP2 (0.43) USP2HTTNCOA1NCOA3DYRK1A
SCHEMBL261803 0.80 MAOA (0.40) USP2HTTNCOA1NCOA3DYRK1A
SCHEMBL23380706 0.80 USP2 (0.39) USP2HTTNCOA1NCOA3DYRK1A
SCHEMBL16640344 0.79 ACHE (0.46) USP2HTTNCOA1NCOA3DYRK1A
SCHEMBL23380302 0.76 USP2 (0.37) USP2HTTNCOA1NCOA3DYRK1A
SCHEMBL13316577 0.76 MAOA (0.37) USP2HTTNCOA1NCOA3DYRK1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11189808-B2 Platinum complexes and devices ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) 2021-11-30 US disclosed
US-20200152891-A1 PLATINUM COMPLEXES AND DEVICES UNIV ARIZONA STATE (US) 2020-05-14 US disclosed
US-10566553-B2 Platinum complexes and devices ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) 2020-02-18 US disclosed
US-9947881-B2 Platinum complexes and devices ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) 2018-04-17 US disclosed
US-20170012224-A1 PLATINUM COMPLEXES AND DEVICES ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY 2017-01-12 US disclosed
US-9385329-B2 Platinum complexes and devices Arizona Board of Regents on behalf of Arizona State University and Universal Display Corporation (US) 2016-07-05 US disclosed
US-20150105556-A1 PLATINUM COMPLEXES AND DEVICES ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY 2015-04-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11189808-B2 Platinum complexes and devices OXA1L, OCIAD1, OCIAD2 USP2 4612/4885HTT 2065/4885NCOA1 423/4885
US-10566553-B2 Platinum complexes and devices OXA1L, OCIAD1, OCIAD2 USP2 4612/4885HTT 2065/4885NCOA1 423/4885
US-20200152891-A1 PLATINUM COMPLEXES AND DEVICES OXA1L, OCIAD1, OCIAD2 USP2 4612/4885HTT 2065/4885NCOA1 423/4885
US-20170012224-A1 PLATINUM COMPLEXES AND DEVICES OXA1L, OCIAD1, OCIAD2 USP2 4612/4885HTT 2065/4885NCOA1 423/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.