Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.46 |
| ▸ | BCHE | P06276 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | CASP7 | P55210 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | NPY5R | Q15761 | 3/20 | 0.44 |
| ▸ | NFATC1 | O95644 | 1/20 | 0.44 |
| ▸ | GSK3B | P49841 | 1/20 | 0.44 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 4/20 | 0.42 |
| ▸ | MAOB | P27338 | 4/20 | 0.42 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16640338 | 0.91 | DYRK1A (0.50) | ACHEBCHETDP1NPY5RNFATC1 | |
| SCHEMBL16640343 | 0.89 | MAOA (0.54) | ACHEBCHEMAPTTSHRMAPK1 | |
| SCHEMBL16640336 | 0.87 | DYRK1A (0.45) | ACHEBCHEMAPTTSHRMAPK1 | |
| SCHEMBL14659643 | 0.86 | MAOA (0.41) | ACHEMAPTTSHRMAPK1CASP1 | |
| SCHEMBL12383079 | 0.83 | MAOA (0.42) | ACHEMAOAMAOBIDO1HPGD | |
| SCHEMBL150044 | 0.82 | BCHE (0.59) | ACHEBCHEMAPTTSHRMAPK1 | |
| SCHEMBL29780042 | 0.82 | BCHE (0.59) | ACHEBCHEMAPTTSHRMAPK1 | |
| SCHEMBL16099930 | 0.81 | ROCK2 (0.39) | ACHEMAPTTSHRMAPK1CASP1 | |
| SCHEMBL16640326 | 0.80 | USP2 (0.40) | MAPTTSHRMAPK1CASP1CASP7 | |
| SCHEMBL16640342 | 0.80 | CDK4 (0.41) | MAPTTSHRMAPK1CASP1CASP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240025878-A1 | MDM2 DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. | 2024-01-25 | — | — | US | disclosed |
| US-20240024318-A1 | SMARCA DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. | 2024-01-25 | — | — | US | disclosed |
| US-11746120-B2 | Stat degraders and uses thereof | KYMERA THERAPEUTICS, INC. (US) | 2023-09-05 | — | — | US | disclosed |
| US-20230234953-A1 | IRAK DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. | 2023-07-27 | — | — | US | disclosed |
| US-20230219945-A1 | IRAK DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. | 2023-07-13 | — | — | US | disclosed |
| US-11679109-B2 | SMARCA degraders and uses thereof | KYMERA THERAPEUTICS, INC. (US) | 2023-06-20 | — | — | US | disclosed |
| US-11542260-B2 | Composition of matter for use in organic light-emitting diodes | KYULUX, INC. (JP) | 2023-01-03 | — | — | US | disclosed |
| US-11189808-B2 | Platinum complexes and devices | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2021-11-30 | — | — | US | disclosed |
| US-20210066613-A1 | COMPOSITION OF MATTER FOR USE IN ORGANIC LIGHT-EMITTING DIODES | KYULUX, INC. (JP) | 2021-03-04 | — | — | US | disclosed |
| US-20200190100-A1 | ORGANIC COMPOUND, AND ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DISPLAY DEVICE INCLUDING THE SAME | LG DISPLAY CO., LTD. (KR) | 2020-06-18 | — | — | US | disclosed |
| WO-2019191454-A1 | COMPOSITION OF MATTER FOR USE ORGANIC LIGHT-EMITTING DIODES | KYULUX, INC. (JP) | 2019-10-03 | — | — | WO | disclosed |
| US-20190233412-A1 | COMPOSITION OF MATTER FOR USE IN ORGANIC LIGHT-EMITTING DIODES | Kyulux North America, Inc. | 2019-08-01 | — | — | US | disclosed |
| US-20190173019-A1 | COMPOSITION OF MATTER FOR USE IN ORGANIC LIGHT-EMITTING DIODES | Kyulux North America, Inc. | 2019-06-06 | — | — | US | disclosed |
| US-20190173017-A1 | COMPOSITION OF MATTER FOR USE IN ORGANIC LIGHT-EMITTING DIODES | Kyulux North America, Inc. | 2019-06-06 | — | — | US | disclosed |
| US-9947881-B2 | Platinum complexes and devices | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2018-04-17 | — | — | US | disclosed |
| US-20170012224-A1 | PLATINUM COMPLEXES AND DEVICES | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY | 2017-01-12 | — | — | US | disclosed |
| US-9385329-B2 | Platinum complexes and devices | Arizona Board of Regents on behalf of Arizona State University and Universal Display Corporation (US) | 2016-07-05 | — | — | US | disclosed |
| CN-104755078-A | Application of harmine derivatives in preparation of antimicrobial agents | XINJIANG HUASHIDAN PHARMACEUTICAL RES CO LTD | 2015-07-01 | — | — | CN | disclosed |
| US-20150105556-A1 | PLATINUM COMPLEXES AND DEVICES | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY | 2015-04-16 | — | — | US | disclosed |
| CN-103070862-A | Application of harmine derivative in preparation of antibacterial drugs | XINJIANG HUASHIDAN PHARMACEUTICAL RES CO LTD | 2013-05-01 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (14 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11189808-B2 | Platinum complexes and devices | OXA1L, OCIAD1, OCIAD2 | ACHE 3544/4885BCHE 3371/4885MAPT 1431/4885 |
| US-20190173019-A1 | COMPOSITION OF MATTER FOR USE IN ORGANIC LIGHT-EMITTING DIODES | CRY2, ALDH1A2, CYBA | ACHE 535/4885BCHE 1873/4885MAPT 256/4885 |
| US-20240025878-A1 | MDM2 DEGRADERS AND USES THEREOF | MDM2, TP53, MDM4 | ACHE 2690/4885BCHE 2514/4885MAPT 1460/4885 |
| US-20230234953-A1 | IRAK DEGRADERS AND USES THEREOF | IRAK2, IRAK3, IRAK1 | ACHE 2778/4885BCHE 2634/4885MAPT 2459/4885 |
| US-11542260-B2 | Composition of matter for use in organic light-emitting diodes | CRY2, NDUFV3, SLCO1B3 | ACHE 353/4885BCHE 1528/4885MAPT 166/4885 |
| US-20190233412-A1 | COMPOSITION OF MATTER FOR USE IN ORGANIC LIGHT-EMITTING DIODES | CRY2, NDUFV3, SLCO1B3 | ACHE 353/4885BCHE 1528/4885MAPT 166/4885 |
| US-20240024318-A1 | SMARCA DEGRADERS AND USES THEREOF | SMARCA1, SMARCA2, SMARCC2 | ACHE 2091/4885BCHE 1041/4885MAPT 3823/4885 |
| US-20200190100-A1 | ORGANIC COMPOUND, AND ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DISPLAY DEVICE INCLUDING THE SAME | OCIAD1, OCIAD2, DRD1 | ACHE 2073/4885BCHE 3758/4885MAPT 941/4885 |
| US-20190173017-A1 | COMPOSITION OF MATTER FOR USE IN ORGANIC LIGHT-EMITTING DIODES | CRY2, ALDH1A2, CYBA | ACHE 535/4885BCHE 1873/4885MAPT 256/4885 |
| US-11746120-B2 | Stat degraders and uses thereof | STAT4, STAT1, STAT3 | ACHE 1933/4885BCHE 1281/4885MAPT 3167/4885 |
| US-20230219945-A1 | IRAK DEGRADERS AND USES THEREOF | IRAK2, IRAK3, IRAK1 | ACHE 2778/4885BCHE 2634/4885MAPT 2459/4885 |
| US-11679109-B2 | SMARCA degraders and uses thereof | SMARCA1, SMARCA2, SMARCC2 | ACHE 2091/4885BCHE 1041/4885MAPT 3823/4885 |
| US-20170012224-A1 | PLATINUM COMPLEXES AND DEVICES | OXA1L, OCIAD1, OCIAD2 | ACHE 3544/4885BCHE 3371/4885MAPT 1431/4885 |
| US-20210066613-A1 | COMPOSITION OF MATTER FOR USE IN ORGANIC LIGHT-EMITTING DIODES | CRY2, CYBA, NDUFV3 | ACHE 652/4885BCHE 2441/4885MAPT 152/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.