SCHEMBL16640716

SCHEMBL16640716

C=C1OC(=O)c2cc(N=Nc3ccc4c(c3)C(=O)OC4=O)ccc21

nearest known ligand 0.58

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.40
ALOX15 P16050 1/20 0.40
ALDH1A1 P00352 3/20 0.40
TYMS P04818 1/20 0.34
CA12 O43570 1/20 0.31
CA1 P00915 1/20 0.31
CA4 P22748 1/20 0.31
CA7 P43166 1/20 0.31
MAPT P10636 1/20 0.30
RXFP1 Q9HBX9 1/20 0.30
KDM4E B2RXH2 2/20 0.30
HPGD P15428 2/20 0.30
L3MBTL1 Q9Y468 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10339047 0.89 ALOX15 (0.50) TDP1ALOX15ALDH1A1TYMSCA12
SCHEMBL9611209 0.89 ALOX15 (0.50) TDP1ALOX15ALDH1A1TYMSCA12
SCHEMBL13907658 0.79 TDP1 (0.44) TDP1ALOX15ALDH1A1TYMSCA12
SCHEMBL24080677 0.79 GRM5 (0.45) TDP1ALOX15ALDH1A1
SCHEMBL14492052 0.75 TDP1 (0.40) TDP1ALOX15ALDH1A1TYMSCA12
SCHEMBL17343179 0.75 MAOA (0.45) TDP1ALOX15ALDH1A1MAPTL3MBTL1
SCHEMBL24080674 0.75 GRM5 (0.45) TDP1ALOX15ALDH1A1
SCHEMBL12559908 0.75 TDP1 (0.48) TDP1ALOX15ALDH1A1TYMSCA12
SCHEMBL9480950 0.74 TDP1 (0.46) TDP1ALOX15ALDH1A1TYMSCA12
SCHEMBL10080803 0.74 TDP1 (0.43) TDP1ALOX15ALDH1A1TYMSKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180127655-A1 LIQUID CRYSTAL ALIGNING AGENTS FOR FORMING PHOTO-ALIGNING LIQUID CRYSTAL ALIGNMENT LAYERS, LIQUID CRYSTAL ALIGNMENT LAYERS AND LIQUID CRYSTAL DISPLAY DEVICES USING THE SAME JNC CORPORATION (JP) 2018-05-10 US disclosed
US-9909065-B2 Liquid crystal aligning agents for forming photo-aligning liquid crystal alignment layers, liquid crystal alignment layers and liquid crystal display devices using the same JNC CORPORATION (JP) 2018-03-06 US disclosed
US-20170327743-A1 LIQUID CRYSTAL DISPLAY DEVICE AND METHOD FOR MANUFACTURING SAME JNC CORP (JP) 2017-11-16 US disclosed
US-9796927-B2 Liquid crystal aligning agents for forming photo-aligning liquid crystal alignment layers, liquid crystal alignment layers and liquid crystal display devices using the same JNC CORPORATION (JP) 2017-10-24 US disclosed
US-9771519-B2 Liquid crystal display device and method for manufacturing same JNC CORPORATION (JP) 2017-09-26 US disclosed
US-20150275089-A1 LIQUID CRYSTAL DISPLAY ELEMENT AND METHOD FOR MANUFACTURING SAME JNC PETROCHEMICAL CORPORATION (JP) 2015-10-01 US disclosed
US-20150105503-A1 LIQUID CRYSTAL ALIGNING AGENTS FOR FORMING PHOTO-ALIGNING LIQUID CRYSTAL ALIGNMENT LAYERS, LIQUID CRYSTAL ALIGNMENT LAYERS AND LIQUID CRYSTAL DISPLAY DEVICES USING THE SAME JNC PETROCHEMICAL CORPORATION (JP) 2015-04-16 US disclosed