SCHEMBL9480950

SCHEMBL9480950

O=C=Nc1ccc2c(c1)C(=O)OC2=O

nearest known ligand 0.46

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.46
MAPK1 P28482 1/20 0.46
CYP3A4 P08684 3/20 0.43
ALOX15 P16050 1/20 0.43
TRPA1 O75762 1/20 0.43
ALDH1A1 P00352 1/20 0.42
CYP1A2 P05177 1/20 0.40
TSHR P16473 1/20 0.39
TYMS P04818 2/20 0.36
CA12 O43570 3/20 0.32
CA7 P43166 3/20 0.32
CA1 P00915 2/20 0.32
CA4 P22748 1/20 0.32
CA2 P00918 1/20 0.30
CA9 Q16790 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10339047 0.84 ALOX15 (0.50) TDP1ALOX15ALDH1A1TYMSCA12
SCHEMBL9611209 0.84 ALOX15 (0.50) TDP1ALOX15ALDH1A1TYMSCA12
SCHEMBL9064366 0.83 MIF (0.42) TDP1CYP3A4ALOX15ALDH1A1CYP1A2
SCHEMBL28448245 0.79 TDP1 (0.56) TDP1MAPK1CYP3A4TRPA1ALDH1A1
SCHEMBL28562992 0.79 TDP1 (0.56) TDP1MAPK1CYP3A4TRPA1ALDH1A1
SCHEMBL12559908 0.78 TDP1 (0.48) TDP1MAPK1CYP3A4ALOX15ALDH1A1
SCHEMBL940920 0.78 MAPK1 (0.50) TDP1MAPK1CYP3A4TRPA1ALDH1A1
SCHEMBL542807 0.78 MAPK1 (0.50) TDP1MAPK1CYP3A4TRPA1ALDH1A1
SCHEMBL11351193 0.77 CYP2C19 (0.50) TDP1MAPK1CYP3A4ALOX15TRPA1
SCHEMBL8940394 0.76 ALOX15 (0.46) TDP1ALOX15ALDH1A1TYMSCA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0371697-B1 Improvements in or relating to polymeric compounds DU PONT (US) 1993-10-20 EP claimed
EP-0412731-A1 Improvements in or relating to bakeable aqueous photopolymers Du Pont (UK) Limited (GB) 1991-02-13 EP claimed
EP-0371697-A2 Improvements in or relating to polymeric compounds E.I. DU PONT DE NEMOURS AND COMPANY (US) 1990-06-06 EP claimed
JP-2212503-A None JP disclosed
CN-114479381-B Preparation method of PET (polyethylene terephthalate) foaming beads for molding 无锡会通轻质材料股份有限公司 2024-01-30 CN disclosed
US-20220332962-A1 POLYMER LAYERS BY REACTIVE PRINTING Heraeus Deutschland GmbH & Co. KG (DE) 2022-10-20 US disclosed
EP-4028448-A1 POLYMER LAYERS BY REACTIVE PRINTING Heraeus Deutschland GmbH & Co. KG (DE) 2022-07-20 EP disclosed
CN-114479381-A Method for preparing PET expanded beads for molding 无锡会通轻质材料股份有限公司 2022-05-13 CN disclosed
WO-2021048219-A1 POLYMER LAYERS BY REACTIVE PRINTING HERAEUS DEUTSCHLAND GMBH & CO KG (DE) 2021-03-18 WO disclosed
EP-3789425-A1 POLYMER LAYERS BY REACTIVE PRINTING Heraeus Deutschland GmbH & Co KG (DE) 2021-03-10 EP disclosed
US-9917032-B2 Conductive thermal compositions, uses thereof, and methods for their preparation EMPIRE TECHNOLOGY DEVELOPMENT LLC (US) 2018-03-13 US disclosed
US-20160033213-A1 CONDUCTIVE THERMAL COMPOSITIONS, USES THEREOF, AND METHODS FOR THEIR PREPARATION CRESTLINE DIRECT FINANCE, L.P. 2016-02-04 US disclosed
EP-0371697-B1 Improvements in or relating to polymeric compounds DU PONT (US) 1993-10-20 EP disclosed
US-5238777-A Resin containing light sensitive azide groups, further reacted with anhydride material to generate carboxylic and sulfonic acid groups; lithography DUPONT (U.K.) LIMITED (GB) 1993-08-24 US disclosed
US-4994530-A Polymeric compounds E. I. DU PONT DE NEMOURS AND COMPANY (INC.) (US) 1991-02-19 US disclosed
JP-H02212503-A IMPROVEMENT OF POLYMER COMPOUND E I DU PONT DE NEMOURS & CO 1990-08-23 JP disclosed
EP-0371697-A2 Improvements in or relating to polymeric compounds E.I. DU PONT DE NEMOURS AND COMPANY (US) 1990-06-06 EP disclosed
US-4391751-A Phthalic anhydride derivatives THE UPJOHN COMPANY (US) 1983-07-05 US disclosed
US-3951922-A Process for preparing polyimides from derivatives of phthalic anhydride THE UPJOHN COMPANY (US) 1976-04-20 US disclosed
US-3951922-A Process for preparing polyimides from derivatives of phthalic anhydride THE UPJOHN COMPANY (US) 1976-04-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160033213-A1 CONDUCTIVE THERMAL COMPOSITIONS, USES THEREOF, AND METHODS FOR THEIR PREPARATION GJB2, HCN2, KCNN2 TDP1 1262/4885MAPK1 2858/4885CYP3A4 4009/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.