Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.32 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.32 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.31 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.30 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.30 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16633013 | 0.90 | PTPN5 (0.33) | PTGS2 | |
| SCHEMBL16632670 | 0.89 | MERTK (0.33) | PTGS2 | |
| SCHEMBL21906628 | 0.88 | CAMKK2 (0.31) | — | |
| SCHEMBL15852229 | 0.85 | CYP1B1 (0.32) | PSMB5 | |
| SCHEMBL15852237 | 0.84 | PDK2 (0.30) | PDK2PDK4 | |
| SCHEMBL20909138 | 0.84 | PTGS2 (0.32) | PTGS2 | |
| SCHEMBL15852228 | 0.83 | PTGS2 (0.33) | PTGS2PDK2PDK4 | |
| SCHEMBL15852349 | 0.83 | — | — | |
| SCHEMBL15852342 | 0.83 | — | — | |
| SCHEMBL14295542 | 0.82 | CEL (0.33) | PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9293712-B2 | Disubstituted pyrene compounds with amino group containing ortho aryl group and devices containing the same | UNIVERSAL DISPLAY CORPORATION (US) | 2016-03-22 | — | — | US | disclosed |
| US-20150102321-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | UNIVERSAL DISPLAY CORPORATION | 2015-04-16 | — | — | US | disclosed |