Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.41 |
| ▸ | MAPK10 | P53779 | 5/20 | 0.40 |
| ▸ | MAPK8 | P45983 | 4/20 | 0.40 |
| ▸ | MAPK13 | O15264 | 2/20 | 0.40 |
| ▸ | MAPK12 | P53778 | 2/20 | 0.40 |
| ▸ | MAPK11 | Q15759 | 2/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.40 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HPGDS | O60760 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | HTR1B | P28222 | 1/20 | 0.39 |
| ▸ | HTR1F | P30939 | 1/20 | 0.39 |
| ▸ | SMO | Q99835 | 4/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8777302 | 0.88 | MAOB (0.46) | MAOBTNIKMAPK10MAPK8MAPK13 | |
| SCHEMBL1664796 | 0.86 | MAOB (0.45) | MAOBTNIKMAPK10MAPK8MAPK13 | |
| SCHEMBL18745971 | 0.85 | MAOB (0.47) | MAOBTNIKMAPK10MAPK8MAPK13 | |
| SCHEMBL1663848 | 0.85 | TNIK (0.47) | MAOBTNIKMAPK10MAPK8MAPK13 | |
| SCHEMBL8777699 | 0.85 | TNIK (0.51) | MAOBTNIKMAPK10MAPK8MAPK13 | |
| SCHEMBL1663344 | 0.85 | MAOB (0.56) | MAOBTNIKMAPK10MAPK8MAPK13 | |
| SCHEMBL1664175 | 0.84 | MAOB (0.49) | MAOBTNIKMAPK10MAPK8MAPK13 | |
| SCHEMBL1666463 | 0.84 | MAPT (0.52) | MAOBTNIKMAPK10MAPK8MAPK13 | |
| SCHEMBL1664924 | 0.84 | MAOB (0.46) | MAOBTNIKMAPK10MAPK8MAPK13 | |
| SCHEMBL8771617 | 0.84 | MGLL (0.46) | MAOBTNIKMAPK10MAPK8MAPK13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2488486-A1 | HEMATOPOIETIC GROWTH FACTOR MIMETIC SMALL MOLECULE COMPOUNDS AND THEIR USES | Ligand Pharmaceuticals Inc. (US) | 2012-08-22 | — | — | EP | disclosed |
| WO-2011046954-A1 | HEMATOPOIETIC GROWTH FACTOR MIMETIC SMALL MOLECULE COMPOUNDS AND THEIR USES | LIGAND PHARMACEUTICALS INC. (US) | 2011-04-21 | — | — | WO | disclosed |