Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.54 |
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.54 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | MAP2K1 | Q02750 | 4/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.50 |
| ▸ | MAP2K2 | P36507 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | RAF1 | P04049 | 1/20 | 0.50 |
| ▸ | BRAF | P15056 | 1/20 | 0.50 |
| ▸ | AKT1 | P31749 | 1/20 | 0.50 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.50 |
| ▸ | MAPKAPK5 | Q8IW41 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetonitrile SCHEMBL1027021 | 0.94 | CYP3A4 (0.48) | MAPTMEN1KMT2ANPSR1APOBEC3G | |
| SCHEMBL10801406 | 0.82 | USP2 (0.42) | MAPTMEN1KMT2ANPSR1APOBEC3G | |
| SCHEMBL8763537 | 0.82 | USP2 (0.42) | MAPTMEN1KMT2ANPSR1APOBEC3G | |
| SCHEMBL9751834 | 0.73 | USP2 (0.37) | MAPTMEN1KMT2ANPSR1CYP3A4 | |
| SCHEMBL3307820 | 0.73 | USP2 (0.37) | MAPTMEN1KMT2ANPSR1CYP3A4 | |
| SCHEMBL11373902 | 0.73 | USP2 (0.47) | MAPTMEN1KMT2ANPSR1APOBEC3G | |
| SCHEMBL11346446 | 0.73 | MEN1 (0.52) | MAPTMEN1KMT2ANPSR1APOBEC3G | |
| SCHEMBL10640406 | 0.72 | — | — | |
| SCHEMBL11173991 | 0.72 | USP2 (0.56) | MAPTCYP3A4CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL25142154 | 0.71 | MYC (0.40) | MAPTCYP3A4CYP1A2CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0073965-B1 | DYES OF THE PHTALOCYANINE SERIES, THEIR PREPARATION AND THEIR USE | CASSELLA Aktiengesellschaft (DE) | 1984-10-10 | — | — | EP | claimed |
| US-4461622-A | Dyestuffs of the phthalocyanine series, their preparation and their use on cellulose | CASSELLA AKTIENGESELLSCHAFT (DE) | 1984-07-24 | — | — | US | claimed |
| EP-0004606-B1 | PROCESS FOR PREPARING ANILINE COMPOUNDS | ETHYL CORPORATION (US) | 1982-03-10 | — | — | EP | claimed |
| CN-111741951-B | Amide compound or salt thereof, agricultural/horticultural fungicide containing the same, and method for using the same | 日本农药株式会社 | 2023-08-18 | — | — | CN | disclosed |
| US-20230203081-A1 | LINCOSAMIDE ANTIBIOTICS AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2023-06-29 | — | — | US | disclosed |
| CN-107426999-B | Pyridine amide compounds having fungicidal activity | 美国陶氏益农公司 | 2023-01-20 | — | — | CN | disclosed |
| CN-114144419-A | Oxazepinotrienone derivative, agricultural or horticultural insecticide containing the derivative, and method of using the same | 日本农药株式会社 | 2022-03-04 | — | — | CN | disclosed |
| US-8466321-B2 | 4-(trichloromethylthio) anilines, method for production thereof, and method for producing 4-(trifluoromethylthio) anilines | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2013-06-18 | — | — | US | disclosed |
| EP-2174929-B1 | 4-(TRICHLOROMETHYLTHIO)ANILINE, METHOD FOR PRODUCING THE SAME, AND METHOD FOR PRODUCING 4-(TRIFLUOROMETHYLTHIO)ANILINE | SUMITOMO CHEMICAL CO (JP) | 2013-03-27 | — | — | EP | disclosed |
| US-8399707-B2 | 4-(trichloromethylthio) anilines, method for production thereof, and method for producing 4-(trifluoromethylthio) anilines | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2013-03-19 | — | — | US | disclosed |
| US-20120245388-A1 | 4-(TRICHLOROMETHYLTHIO) ANILINES, METHOD FOR PRODUCTION THEREOF, AND METHOD FOR PRODUCING 4-(TRIFLUOROMETHYLTHIO) ANILINES | SUMITOMO CHEMICAL COMPANY, LIMITED | 2012-09-27 | — | — | US | disclosed |
| US-20070203167-A1 | 2-(Hetero)-aryl substituted tetrahydrochinoline | MERCK PATENT GMBH (DE) | 2007-08-30 | — | — | US | disclosed |
| EP-1761515-A1 | 2-(HETERO-)ARYL SUBSTITUTED TETRAHYDROQUINOLINE DERIVATIVES | MERCK PATENT GmbH (DE) | 2007-03-14 | — | — | EP | disclosed |
| WO-2005063735-A1 | 2-(HETERO)-ARYL-SUBSTITUTED TETRAHYDROQUINOLINE DERIVATIVES | MERCK PATENT GMBH (DE) | 2005-07-14 | — | — | WO | disclosed |
| US-20050031528-A1 | Carbon black | UBS LIMITED (GB) | 2005-02-10 | — | — | US | disclosed |
| US-6689909-B1 | TREATMENT OF DISEASE STATE SELECTED FROM THE GROUP CONSISTING OF DIABETES MELLITUS, PERIPHERAL VASCULAR DISEASE AND MYOCARDIAL ISCHAEMIA | ASTRAZENECA AB (SE) | 2004-02-10 | — | — | US | disclosed |
| US-4461622-A | Dyestuffs of the phthalocyanine series, their preparation and their use on cellulose | CASSELLA AKTIENGESELLSCHAFT (DE) | 1984-07-24 | — | — | US | disclosed |
| US-4331817-A | SULFIDING IN THE PRESENCE OF HALOGENS | MINNESOTA MINING AND MANUFACTURING CO. (US) | 1982-05-25 | — | — | US | disclosed |
| US-4111879-A | RESIN AND AN N-ARYL-MALEIMIDE | IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 1978-09-05 | — | — | US | disclosed |
| US-3998801-A | MONOAZO DYES; POLYAMIDES; RED TO VIOLET SHADES | EASTMAN KODAK COMPANY (US) | 1976-12-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120245388-A1 | 4-(TRICHLOROMETHYLTHIO) ANILINES, METHOD FOR PRODUCTION THEREOF, AND METHOD FOR PRODUCING 4-(TRIFLUOROMETHYLTHIO) ANILINES | PFAS, AFF4, ACSL4 | MAPT 2366/4885MEN1 3764/4885KMT2A 1121/4885 |
| US-20070203167-A1 | 2-(Hetero)-aryl substituted tetrahydrochinoline | NCOR1, CCNT2, NCOR2 | MAPT 3898/4885MEN1 576/4885KMT2A 644/4885 |
| US-20230203081-A1 | LINCOSAMIDE ANTIBIOTICS AND USES THEREOF | NPEPPS, TLR7, ASNS | MAPT 2283/4885MEN1 3882/4885KMT2A 2871/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.