Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | PRKCZ | Q05513 | 9/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.57 |
| ▸ | HPGD | P15428 | 3/20 | 0.57 |
| ▸ | MAPT | P10636 | 6/20 | 0.56 |
| ▸ | GAA | P10253 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.56 |
| ▸ | MEN1 | O00255 | 4/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.56 |
| ▸ | MPI | P34949 | 1/20 | 0.56 |
| ▸ | USP2 | O75604 | 1/20 | 0.56 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.55 |
| ▸ | CASP1 | P29466 | 1/20 | 0.55 |
| ▸ | CASP7 | P55210 | 1/20 | 0.55 |
| ▸ | PRKCI | P41743 | 2/20 | 0.53 |
| ▸ | FHIT | P49789 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL162443 | 0.83 | ALDH1A1 (0.63) | ALDH1A1SMN1; SMN2MAPK1POLBPRKCZ | |
| SCHEMBL10532585 | 0.81 | ALDH1A1 (0.75) | ALDH1A1SMN1; SMN2MAPK1POLBPRKCZ | |
| SCHEMBL8907488 | 0.81 | ALDH1A1 (0.61) | ALDH1A1SMN1; SMN2MAPK1POLBPRKCZ | |
| SCHEMBL4102678 | 0.81 | ALDH1A1 (0.61) | ALDH1A1SMN1; SMN2MAPK1POLBPRKCZ | |
| Chloromethane SCHEMBL21192469 | 0.80 | ALDH1A1 (0.60) | ALDH1A1SMN1; SMN2MAPK1POLBPRKCZ | |
| SCHEMBL7613063 | 0.80 | PRKCZ (0.63) | ALDH1A1SMN1; SMN2MAPK1POLBPRKCZ | |
| SCHEMBL25522293 | 0.79 | ALDH1A1 (0.58) | ALDH1A1SMN1; SMN2MAPK1POLBPRKCZ | |
| SCHEMBL27969855 | 0.79 | ALDH1A1 (0.58) | ALDH1A1SMN1; SMN2MAPK1POLBPRKCZ | |
| SCHEMBL8907155 | 0.79 | PRKCZ (0.60) | ALDH1A1SMN1; SMN2MAPK1POLBPRKCZ | |
| SCHEMBL24302935 | 0.78 | ALDH1A1 (0.57) | ALDH1A1SMN1; SMN2MAPK1POLBPRKCZ |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015052065-A1 | CYCLIC THIENOURACIL-CARBOXAMIDES AND USE THEREOF | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2015-04-16 | — | — | WO | disclosed |