Sugi Predict

Sugi Predict / Compounds / SCHEMBL162443

SCHEMBL162443

SCHEMBL162443

CCOC(=O)c1c(C)csc1N

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 8/20 0.63
▸ SMN1; SMN2 Q16637 2/20 0.63
▸ MAPK1 P28482 2/20 0.63
▸ POLB P06746 1/20 0.63
▸ PRKCZ Q05513 8/20 0.61
▸ HSD17B10 Q99714 5/20 0.60
▸ HPGD P15428 3/20 0.60
▸ MAPT P10636 6/20 0.59
▸ GAA P10253 3/20 0.59
▸ ADRA2A P08913 1/20 0.59
▸ ADRA2B P18089 1/20 0.59
▸ ADRA2C P18825 1/20 0.59
▸ KMT2A Q03164 5/20 0.58
▸ MEN1 O00255 4/20 0.58
▸ ALOX15 P16050 3/20 0.58
▸ MPI P34949 1/20 0.58
▸ USP2 O75604 1/20 0.58
▸ KEAP1 Q14145 1/20 0.58
▸ TDP1 Q9NUW8 2/20 0.57
▸ CASP1 P29466 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Chloromethane SCHEMBL21192469 0.97 ALDH1A1 (0.60) ALDH1A1SMN1; SMN2MAPK1POLBPRKCZ
SCHEMBL10532585 0.84 ALDH1A1 (0.75) ALDH1A1SMN1; SMN2MAPK1POLBPRKCZ
SCHEMBL8907488 0.84 ALDH1A1 (0.61) ALDH1A1SMN1; SMN2MAPK1POLBPRKCZ
SCHEMBL4102678 0.84 ALDH1A1 (0.61) ALDH1A1SMN1; SMN2MAPK1POLBPRKCZ
SCHEMBL7613063 0.83 PRKCZ (0.63) ALDH1A1SMN1; SMN2MAPK1POLBPRKCZ
SCHEMBL16643764 0.83 ALDH1A1 (0.60) ALDH1A1SMN1; SMN2MAPK1POLBPRKCZ
SCHEMBL13602353 0.81 ADRA2A (0.58) ALDH1A1SMN1; SMN2MAPK1POLBPRKCZ
SCHEMBL1041240 0.81 ALDH1A1 (0.59) ALDH1A1SMN1; SMN2MAPK1POLBPRKCZ
SCHEMBL8907155 0.81 PRKCZ (0.60) ALDH1A1SMN1; SMN2MAPK1POLBPRKCZ
SCHEMBL25522293 0.81 ALDH1A1 (0.58) ALDH1A1SMN1; SMN2MAPK1POLBPRKCZ

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 332 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115920647-A Novel nanofiltration concentration separation flux stabilizer and preparation method thereof 杭州尚善若水环保科技有限公司 2023-04-07 — — CN claimed
US-20250295652-A1 Inhibitors of Molluscum Contagiosum Infection and Methods Using the Same UNIV PENNSYLVANIA (US) 2025-09-25 — — US disclosed
WO-2025108404-A1 HETEROCYCLIC COMPOUND OF BIFUNCTIONAL CHIMERA FOR TARGETED DEGRADATION OF ANDROGEN RECEPTOR AND USE THEREOF 广东东阳光药业股份有限公司 2025-05-30 — — WO disclosed
CN-120025326-A Heterocyclic compound of bifunctional chimera for targeting and degrading androgen receptor and application thereof 广东东阳光药业股份有限公司 2025-05-23 — — CN disclosed
CN-119977993-A Solid forms of thienopyrimidinedione ACC inhibitors and methods of making the same 吉利德阿波罗公司 2025-05-13 — — CN disclosed
US-20240408093-A1 HETEROBIFUNCTIONAL COMPOUNDS AND THEIR USE IN TREATING DISEASE HALDA THERAPEUTICS OPCO, INC. 2024-12-12 — — US disclosed
CN-118541359-A Inhibitors of molluscum contagiosum infection and methods of use thereof 宾夕法尼亚大学董事会 2024-08-23 — — CN disclosed
EP-4408833-A1 INHIBITORS OF MOLLUSCUM CONTAGIOSUM INFECTION AND METHODS USING THE SAME The Trustees of The University of Pennsylvania (US) 2024-08-07 — — EP disclosed
WO-2024131942-A1 CYCLOPROPANE TLR7 AND TLR8 INHIBITOR, PREPARATION METHOD THEREFOR, AND USE THEREOF 上海深势唯思科技有限责任公司 2024-06-27 — — WO disclosed
CN-118239959-A Cyclopropane TLR7 and 8 inhibitor and preparation method and application thereof 上海深势唯思科技有限责任公司 2024-06-25 — — CN disclosed
US-4866065-A ANTICONVULSANTS, ANXIOLYTIC AGENTS, HYPNOTICS, AND COGNITION ACTIVATORS A/S FERROSAN (DK) 1989-09-12 — — US disclosed
EP-0311321-A2 Heterocyclic compounds and their preparation and use NOVO NORDISK A/S (DK) 1989-04-12 — — EP disclosed
EP-0291853-A2 Thienon compounds BASF Aktiengesellschaft (DE) 1988-11-23 — — EP disclosed
US-4707550-A N-(substituted thienyl)-N'-(substituted piperazinyl)-ureas ORTHO PHARMACEUTICAL CORPORATION (US) 1987-11-17 — — US disclosed
EP-0244176-A2 Thienopyrimidine-2,4-dione derivatives and intermediates thereof ORTHO PHARMACEUTICAL CORPORATION (US) 1987-11-04 — — EP disclosed
US-4692461-A PLANT PROTECTION BAYER AKTIENGESELLSCHAFT (DE) 1987-09-08 — — US disclosed
EP-0224140-A1 Thienyl urea derivatives BAYER AG (DE) 1987-06-03 — — EP disclosed
US-4670560-A VASODILATING AGENTS, HYPOTENSIVE AGENTS AND/OR CARDIOVASCULAR AGENTS ORTHO PHARMACEUTICAL CORPORATION (US) 1987-06-02 — — US disclosed
US-4221911-A Naphtholactam dyestuffs CIBA-GEIGY CORPORATION (US) 1980-09-09 — — US disclosed
US-4211696-A Disperse monoazo dyestuffs derived from 3,5-dinitro-2-amino thiophene as disazo component and an arylamine coupling component IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) 1980-07-08 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250295652-A1 Inhibitors of Molluscum Contagiosum Infection and Methods Using the Same ITCH, EIF2AK2, TBK1 ALDH1A1 3761/4885SMN1; SMN2 3377/4885MAPK1 2408/4885
US-20240408093-A1 HETEROBIFUNCTIONAL COMPOUNDS AND THEIR USE IN TREATING DISEASE FGFR3, FGFR1, ERBB3 ALDH1A1 4423/4885SMN1; SMN2 4375/4885MAPK1 180/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.