Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.72 |
| ▸ | THRB | P10828 | 1/20 | 0.72 |
| ▸ | MAPT | P10636 | 4/20 | 0.67 |
| ▸ | GAA | P10253 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.60 |
| ▸ | F2 | P00734 | 3/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16644246 | 0.99 | TP53 (0.74) | TP53THRBMAPTGAAALDH1A1 | |
| SCHEMBL16644176 | 0.85 | ALDH1A1 (0.55) | TP53THRBMAPTGAAALDH1A1 | |
| SCHEMBL15246121 | 0.79 | F2 (0.71) | TP53MAPTALDH1A1F2SMN1; SMN2 | |
| SCHEMBL16639849 | 0.77 | TP53 (0.75) | TP53THRBMAPTALDH1A1MEN1 | |
| SCHEMBL27312618 | 0.77 | ALDH1A1 (0.88) | TP53GAAALDH1A1 | |
| SCHEMBL15969432 | 0.77 | MEN1 (0.55) | TP53THRBMAPTALDH1A1MEN1 | |
| SCHEMBL16644215 | 0.77 | F2 (0.58) | TP53MAPTALDH1A1F2SMN1; SMN2 | |
| SCHEMBL15246477 | 0.77 | ALDH1A1 (0.60) | TP53THRBMAPTALDH1A1MEN1 | |
| SCHEMBL9158553 | 0.75 | NR4A2 (0.63) | TP53MAPTALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL18038950 | 0.75 | TP53 (0.52) | TP53THRBMAPTGAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10696692-B2 | Amido-benzyl sulfone and sulfoxide derivates | Valo Health, LLC | 2020-06-30 | — | — | US | disclosed |
| US-20150104384-A1 | AMIDO-BENZYL SULFONE AND SULFOXIDE DERIVATIVES | VALO HEALTH, INC. | 2015-04-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10696692-B2 | Amido-benzyl sulfone and sulfoxide derivates | STS, SQOR, SULT1E1 | TP53 1915/4885THRB 2880/4885MAPT 1118/4885 |
| US-20150104384-A1 | AMIDO-BENZYL SULFONE AND SULFOXIDE DERIVATIVES | STS, SULT1E1, CBS | TP53 2268/4885THRB 3170/4885MAPT 2018/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.