Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 11/20 | 0.74 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15246205 | 0.90 | NAMPT (0.61) | NAMPTALDH1A1MAPTLMNA | |
| SCHEMBL15246146 | 0.82 | NAMPT (1.00) | NAMPT | |
| SCHEMBL16644165 | 0.81 | NAMPT (0.72) | NAMPTALDH1A1MAPTHPGDLMNA | |
| SCHEMBL30167626 | 0.80 | NAMPT (0.87) | NAMPTALDH1A1MAPTHPGDLMNA | |
| SCHEMBL12466816 | 0.80 | NAMPT (0.87) | NAMPTALDH1A1MAPTHPGDLMNA | |
| SCHEMBL12466902 | 0.80 | NAMPT (0.77) | NAMPTALDH1A1MAPT | |
| SCHEMBL16644180 | 0.80 | NAMPT (0.70) | NAMPTALDH1A1MAPTHPGDLMNA | |
| SCHEMBL12466805 | 0.78 | NAMPT (1.00) | NAMPTALDH1A1MAPTHPGD | |
| SCHEMBL16644235 | 0.77 | NAMPT (0.64) | NAMPTALDH1A1MAPTHPGD | |
| SCHEMBL27312618 | 0.76 | ALDH1A1 (0.88) | NAMPTALDH1A1HPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10696692-B2 | Amido-benzyl sulfone and sulfoxide derivates | Valo Health, LLC | 2020-06-30 | — | — | US | disclosed |
| US-20150104384-A1 | AMIDO-BENZYL SULFONE AND SULFOXIDE DERIVATIVES | VALO HEALTH, INC. | 2015-04-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10696692-B2 | Amido-benzyl sulfone and sulfoxide derivates | STS, SQOR, SULT1E1 | NAMPT 459/4885ALDH1A1 2853/4885MAPT 1118/4885 |
| US-20150104384-A1 | AMIDO-BENZYL SULFONE AND SULFOXIDE DERIVATIVES | STS, SULT1E1, CBS | NAMPT 759/4885ALDH1A1 2737/4885MAPT 2018/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.