Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | FGB | P02675 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | THRB | P10828 | 1/20 | 0.56 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.56 |
| ▸ | PPARG | P37231 | 1/20 | 0.56 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.56 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.56 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.56 |
| ▸ | NAMPT | P43490 | 6/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15246125 | 0.92 | ALDH1A1 (0.54) | KMT2AMEN1ALDH1A1MAPTTHRB | |
| SCHEMBL15246118 | 0.91 | ALDH1A1 (0.54) | KMT2AMEN1ALDH1A1MAPTTHRB | |
| SCHEMBL16644184 | 0.84 | HPGD (0.64) | POLBKMT2AMEN1ALDH1A1FGB | |
| SCHEMBL16644189 | 0.80 | TP53 (0.53) | POLBKMT2AMEN1ALDH1A1FGB | |
| SCHEMBL16644220 | 0.79 | NAMPT (0.56) | POLBKMT2AMEN1ALDH1A1FGB | |
| SCHEMBL16639773 | 0.75 | ALDH1A1 (0.62) | POLBKMT2AMEN1ALDH1A1FGB | |
| SCHEMBL16639781 | 0.75 | TP53 (0.56) | POLBKMT2AMEN1ALDH1A1FGB | |
| SCHEMBL24477293 | 0.74 | APOBEC3A (0.50) | KMT2AMEN1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL16639792 | 0.74 | ALDH1A1 (0.61) | POLBKMT2AMEN1ALDH1A1FGB | |
| SCHEMBL16639850 | 0.73 | NAMPT (0.54) | POLBKMT2AMEN1ALDH1A1FGB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150104384-A1 | AMIDO-BENZYL SULFONE AND SULFOXIDE DERIVATIVES | VALO HEALTH, INC. | 2015-04-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150104384-A1 | AMIDO-BENZYL SULFONE AND SULFOXIDE DERIVATIVES | STS, SULT1E1, CBS | POLB 4160/4885KMT2A 2980/4885MEN1 3017/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.