Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APOBEC3A | P31941 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 4/20 | 0.47 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 8/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 7/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | ADORA1 | P30542 | 7/20 | 0.45 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24477299 | 0.83 | ALDH1A1 (0.71) | ALDH1A1KDM4EKMT2AHPGDCYP1A1 | |
| SCHEMBL22472811 | 0.80 | APOBEC3A (0.47) | APOBEC3AALDH1A1KDM4EKMT2AHPGD | |
| SCHEMBL22472753 | 0.79 | APOBEC3A (0.46) | APOBEC3AALDH1A1KDM4EKMT2AHPGD | |
| SCHEMBL15246125 | 0.74 | ALDH1A1 (0.54) | ALDH1A1KDM4EKMT2AHPGDMEN1 | |
| SCHEMBL24477294 | 0.74 | APOBEC3A (0.39) | APOBEC3AALDH1A1KDM4EKMT2AHPGD | |
| SCHEMBL16644239 | 0.74 | POLB (0.56) | ALDH1A1KMT2AMEN1MAPTSMN1; SMN2 | |
| SCHEMBL24477300 | 0.74 | ALDH1A1 (0.72) | ALDH1A1KDM4EKMT2AHPGDCYP1A1 | |
| SCHEMBL15246118 | 0.74 | ALDH1A1 (0.54) | ALDH1A1KDM4EKMT2AHPGDMEN1 | |
| SCHEMBL22767522 | 0.73 | ALDH1A1 (0.41) | APOBEC3AALDH1A1KDM4EKMT2AHPGD | |
| SCHEMBL24477289 | 0.72 | ALDH1A1 (0.43) | ALDH1A1KDM4EKMT2AHPGDCYP1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220169652-A1 | SUBSTITUTED PYRAZOLO[1,5-A]PYRIMIDINES AND THEIR USE IN THE TREATMENT OF MEDICAL DISORDERS | LYSOSOMAL THERAPEUTICS INC. | 2022-06-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220169652-A1 | SUBSTITUTED PYRAZOLO[1,5-A]PYRIMIDINES AND THEIR USE IN THE TREATMENT OF MEDICAL DISORDERS | PARK7, PNP, GAA | APOBEC3A 320/4885ALDH1A1 1213/4885KDM4E 899/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.